{"id":"W2110736523","doi":"10.1128/iai.71.2.676-681.2003","title":"Roles of Sortase in Surface Expression of the Major Protein Adhesin P1, Saliva-Induced Aggregation and Adherence, and Cariogenicity of <i>Streptococcus mutans</i>","year":2003,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sortase; Mutant; Sortase A; Streptococcus mutans; Peptidoglycan; Biology; Bacterial adhesin; Wild type; Complementation; Microbiology; Peptide sequence; Glucosyltransferase; Molecular biology; Biochemistry; Gene; Escherichia coli; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009919854,0.00006762453,0.0001034094,0.00001605705,0.00003549773,0.000004022024,0.000026036,0.0001054569,0.000003519897],"category_scores_gemma":[0.00009172678,0.00005000832,0.00002027294,0.00008835596,0.00008973732,0.000007996708,0.00003735003,0.00006520275,1.41124e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002987635,"about_ca_system_score_gemma":0.00001911754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003724617,"about_ca_topic_score_gemma":0.0001372439,"domain_scores_codex":[0.9995109,0.000121325,0.0001757198,0.00009601788,0.00004578425,0.00005027553],"domain_scores_gemma":[0.9996662,0.000007595163,0.0001426635,0.0001073891,0.00005791898,0.00001827509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004346194,0.00002509736,0.09585538,0.00005429628,0.000004818616,2.353064e-8,0.00006727192,9.550115e-7,0.9030089,0.00001884535,9.530294e-7,0.0009199806],"study_design_scores_gemma":[0.0003237496,0.00009761423,0.168999,0.00005188093,0.000006239197,0.000002129892,0.00003480531,0.000006658254,0.830343,0.00007386974,0.00001776515,0.00004330737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994969,0.0002025198,0.00001560314,0.000006609376,0.0000168288,0.000202378,0.00001581978,0.000001672721,0.00004171331],"genre_scores_gemma":[0.9998417,0.00008116895,0.00003507579,0.000005795917,0.000003684874,0.000004037834,0.00001630473,0.000002861982,0.000009324731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07314359,"threshold_uncertainty_score":0.203928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008287853201400328,"score_gpt":0.2210290740800595,"score_spread":0.2127412208786592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}