{"id":"W2110736523","doi":"10.1128/iai.71.2.676-681.2003","title":"Roles of Sortase in Surface Expression of the Major Protein Adhesin P1, Saliva-Induced Aggregation and Adherence, and Cariogenicity of <i>Streptococcus mutans</i>","year":2003,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sortase; Mutant; Sortase A; Streptococcus mutans; Peptidoglycan; Biology; Bacterial adhesin; Wild type; Complementation; Microbiology; Peptide sequence; Glucosyltransferase; Molecular biology; Biochemistry; Gene; Escherichia coli; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001193652,0.0003573113,0.0001466314,0.0001546645,0.0001292921,0.0003875457,0.0001490295,0.0002388949,0.0003884629],"category_scores_gemma":[0.00016438,0.0001299812,0.0001991225,0.00009817295,0.0001964138,0.0002026601,0.0002910744,0.0004232714,0.0002524747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003453816,"about_ca_system_score_gemma":0.0002813211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009048281,"about_ca_topic_score_gemma":0.0006538912,"domain_scores_codex":[0.9998548,0.00002839504,0.00001595909,0.00002129617,0.00004788834,0.00003162233],"domain_scores_gemma":[0.9998564,0.0000246932,0.00004872979,0.00001469554,0.00002136505,0.00003417219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003816571,0.000006236552,0.0001841499,0.000009212325,0.000001137493,0.00004155428,0.00001653784,0.00001929573,0.9991473,0.00005390652,0.000007913553,0.0004746568],"study_design_scores_gemma":[0.000005647184,0.00009398429,0.008087227,0.000004212272,0.00000833401,0.0005377435,0.00006955193,0.0009742595,0.9892624,0.0000576221,0.0008945332,0.000004380638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983637,0.0003792761,0.0007280497,0.00005611656,0.000005306075,0.000005435537,0.00007339018,0.00002182839,0.0003669364],"genre_scores_gemma":[0.9975526,0.0002387924,0.0008115642,0.00002133803,0.000003083348,0.000009831695,0.0002268249,0.00001122075,0.00112471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009048281,"threshold_uncertainty_score":0.002505898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008287853201400328,"score_gpt":0.2210290740800595,"score_spread":0.2127412208786592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}