{"id":"W2110882632","doi":"10.4049/jimmunol.167.5.2547","title":"Bidirectional Negative Regulation of Human T and Dendritic Cells by CD47 and Its Cognate Receptor Signal-Regulator Protein-α: Down-Regulation of IL-12 Responsiveness and Inhibition of Dendritic Cell Activation","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation; Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"","keywords":"Cell biology; CD47; Biology; Proinflammatory cytokine; T cell; Immune system; Dendritic cell; Interleukin 10; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007829331,0.0001903734,0.00051549,0.0003440549,0.0001912176,0.000007734041,0.00009480659,0.0002810322,0.000108426],"category_scores_gemma":[0.0001059353,0.0001562386,0.00006696441,0.0002032058,0.0006138088,0.0003739739,0.0000633659,0.0002450527,0.000001256763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005414963,"about_ca_system_score_gemma":0.00006619575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000529601,"about_ca_topic_score_gemma":0.000005063723,"domain_scores_codex":[0.9977735,0.0008712072,0.0008977469,0.000164854,0.0001094498,0.0001832075],"domain_scores_gemma":[0.9973601,0.0004269523,0.001444729,0.0001406037,0.0006066946,0.00002090279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001935094,0.0001405335,0.000369905,0.00008552451,0.0001912381,2.335763e-7,0.0008231241,0.00004062201,0.9946223,0.0004115745,0.00005453829,0.00132533],"study_design_scores_gemma":[0.00231079,0.001047078,0.09138267,0.0003372247,0.0001299755,0.0001232202,0.0003733161,0.00003554211,0.9030206,0.001033006,0.00008874806,0.0001179005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994232,0.004734297,0.0002535,0.0001857172,0.000129365,0.000397046,0.0000333163,0.000006656144,0.00002808168],"genre_scores_gemma":[0.9989499,0.0005886913,0.00006277828,0.000008705666,0.00002196864,0.000005989772,0.00003423751,0.00001643887,0.0003112392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09160175,"threshold_uncertainty_score":0.6371224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097194888934725,"score_gpt":0.2262720894247379,"score_spread":0.2153001405353907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}