{"id":"W2110892172","doi":"10.1152/ajpheart.00958.2005","title":"Cells expressing unique Na<sup>+</sup>/Ca<sup>2+</sup>exchange (NCX1) splice variants exhibit different susceptibilities to Ca<sup>2+</sup>overload","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"HEK 293 cells; Molecular biology; Transfection; Ouabain; Gene isoform; Intracellular; Sodium-calcium exchanger; Alternative splicing; Chemistry; Endogeny; Cell culture; Biology; Cell biology; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003122521,0.000264902,0.0003183502,0.000153002,0.000217921,0.0004541178,0.00021841,0.000319904,0.001164965],"category_scores_gemma":[0.0002177613,0.0001457769,0.0003094914,0.0002450497,0.0003717142,0.0002343373,0.0002534198,0.0004680306,0.0004465043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002237762,"about_ca_system_score_gemma":0.0001811522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004693864,"about_ca_topic_score_gemma":0.0006881711,"domain_scores_codex":[0.9997376,0.00002564058,0.00006036849,0.00005714739,0.00007747565,0.00004180981],"domain_scores_gemma":[0.9996773,0.00007671781,0.0001081628,0.00005570486,0.00002883406,0.00005318894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007948414,0.000009452735,0.0004650612,0.00001555122,0.000004220729,0.00005623346,0.00002237918,0.00002207201,0.9988742,0.00006552675,0.00002034121,0.0003654074],"study_design_scores_gemma":[0.00002441299,0.0001677927,0.01660169,0.000004205643,0.00003037553,0.0009532042,0.0001103413,0.0008092455,0.9789058,0.00008687084,0.002294309,0.0000118467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954877,0.0004724545,0.002415001,0.0000983857,0.00003589923,0.00002255857,0.0006767191,0.00006078664,0.0007303546],"genre_scores_gemma":[0.992147,0.0004658401,0.003378975,0.00008634105,0.00001913483,0.00005638131,0.002008869,0.00004115596,0.00179629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001164965,"threshold_uncertainty_score":0.00389725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008474347499117118,"score_gpt":0.2355398126452748,"score_spread":0.2270654651461576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}