{"id":"W2110902454","doi":"10.2174/187221309788489760","title":"CTLA-4Ig: Uses and Future Directions","year":2009,"lang":"en","type":"article","venue":"Recent Patents on Inflammation & Allergy Drug Discovery","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"CD80; Abatacept; CTLA-4; CD86; Immunology; Medicine; Cytotoxic T cell; Rheumatoid arthritis; CD28; Immune system; Co-stimulation; T cell; Computational biology; Antibody; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004346202,0.001006545,0.0009847531,0.001529097,0.000530111,0.002703626,0.001641321,0.004205513,0.01551917],"category_scores_gemma":[0.002352205,0.0002880234,0.00092309,0.001151193,0.001552607,0.005366444,0.001021785,0.002955735,0.004698171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001406155,"about_ca_system_score_gemma":0.002619563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000896381,"about_ca_topic_score_gemma":0.002128637,"domain_scores_codex":[0.9991083,0.0002089234,0.00009123133,0.0001624319,0.0002870485,0.0001421122],"domain_scores_gemma":[0.9979165,0.0007699561,0.0002357015,0.00009314083,0.0005683687,0.000416306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006690469,0.0004201933,0.0007856619,0.002363367,0.00005401152,0.0007582333,0.0001142411,0.0007583327,0.003965872,0.01935062,0.0418856,0.928875],"study_design_scores_gemma":[0.0001827913,0.001342022,0.001367931,0.00266603,0.0001384179,0.003056749,0.0005371676,0.001043509,0.002216406,0.03768172,0.9497071,0.00006017059],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003354266,0.9395894,0.002800237,0.03922039,0.001593616,0.00002626088,0.0001415412,0.0001204563,0.01315396],"genre_scores_gemma":[0.02635147,0.9365154,0.0061991,0.01340154,0.005668253,0.00007994947,0.000287424,0.00003529324,0.01146157],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01551917,"threshold_uncertainty_score":0.05191678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089703861054202,"score_gpt":0.2191888909327949,"score_spread":0.2082918523222528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}