{"id":"W2110924026","doi":"10.1074/jbc.m112234200","title":"α2-HS Glycoprotein/Fetuin, a Transforming Growth Factor-β/Bone Morphogenetic Protein Antagonist, Regulates Postnatal Bone Growth and Remodeling","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bone health and treatments","field":"Medicine","cited_by":217,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Fetuin; Bone morphogenetic protein; Glycoprotein; Bone remodeling; Transforming growth factor; Bone morphogenetic protein 2; Bone morphogenetic protein 7; Bone growth; Cell biology; Endocrinology; Antagonist; Growth factor; Internal medicine; Chemistry; Biology; Medicine; Receptor; Biochemistry; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001050499,0.0004828704,0.000183286,0.0002551443,0.0001109667,0.0001911606,0.0001430929,0.0001816668,0.0005003507],"category_scores_gemma":[0.00008280178,0.0001084232,0.0001587424,0.000104719,0.000340824,0.0001678768,0.0001530045,0.0001974629,0.0002223877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001857439,"about_ca_system_score_gemma":0.0001372131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006687795,"about_ca_topic_score_gemma":0.001247443,"domain_scores_codex":[0.9999204,0.0000173302,0.000007632145,0.00001292892,0.0000272291,0.00001458243],"domain_scores_gemma":[0.9999083,0.00001098633,0.00003263018,0.000007634513,0.000009697436,0.0000307577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006042381,0.00000732525,0.0004941972,0.00001344477,0.000002609498,0.00004789317,0.000007231311,0.00002850329,0.9975914,0.0000619929,0.00001661988,0.001668484],"study_design_scores_gemma":[0.00001986804,0.0003984061,0.01761348,0.000005778847,0.00002316292,0.0007027785,0.00004406454,0.0008531298,0.9766773,0.0001149898,0.003540966,0.000006073033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896848,0.004155381,0.00444259,0.00006432543,0.00001934288,0.00003240068,0.0002072424,0.0001251219,0.001268746],"genre_scores_gemma":[0.9925466,0.002044024,0.002976108,0.00004050223,0.00001000506,0.00002095273,0.0002754154,0.00001905724,0.002067125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006687795,"threshold_uncertainty_score":0.001673818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02827211820356473,"score_gpt":0.2523599062302073,"score_spread":0.2240877880266426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}