{"id":"W2111017518","doi":"10.1161/hypertensionaha.111.190223","title":"Adipocytes Produce Aldosterone Through Calcineurin-Dependent Signaling Pathways","year":2012,"lang":"en","type":"article","venue":"Hypertension","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":366,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Aldosterone; Endocrinology; Internal medicine; Adipocyte; Mineralocorticoid receptor; Aldosterone synthase; Calcineurin; Mineralocorticoid; Angiotensin II; Biology; Adipose tissue; Mesenteric arteries; Receptor; Medicine; Renin–angiotensin system; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002583915,0.0002316045,0.0004196547,0.00008771009,0.0001564403,0.00001658145,0.00006129655,0.0001406039,0.0001745257],"category_scores_gemma":[0.000170818,0.0001709838,0.0001149935,0.0001635189,0.00004645048,0.0002812716,0.00007159842,0.0002213084,0.0005155336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006709853,"about_ca_system_score_gemma":0.00005238666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003396453,"about_ca_topic_score_gemma":0.000001403258,"domain_scores_codex":[0.9982641,0.00005362714,0.0003234009,0.0003392038,0.0005436126,0.0004761077],"domain_scores_gemma":[0.9989139,0.00006085961,0.00007972535,0.0004186849,0.0002388433,0.0002879653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002399439,0.0004384264,0.004592842,0.00004577665,0.00004377079,0.0001235564,0.0003717885,0.000009020034,0.9806148,0.0003565032,0.004386953,0.008776654],"study_design_scores_gemma":[0.004481049,0.0007182514,0.1123046,0.0004379457,0.0005616096,0.005459843,0.0005095524,0.00140159,0.7237795,0.000148193,0.1494994,0.000698443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897398,0.004636294,0.0002125177,0.002088755,0.0004551711,0.0004236226,0.000002914678,0.0001861513,0.002254803],"genre_scores_gemma":[0.992123,0.0001303871,0.002396059,0.00366608,0.0007296987,0.0000121451,0.00004168016,0.0000507376,0.0008501832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2568353,"threshold_uncertainty_score":0.6972519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0913151818532247,"score_gpt":0.2768924922785216,"score_spread":0.1855773104252969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}