{"id":"W2111021925","doi":"10.1517/14712598.5.1.97","title":"Progress in prion vaccines and immunotherapies","year":2005,"lang":"en","type":"review","venue":"Expert Opinion on Biological Therapy","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Epitope; Gene isoform; Virology; Antibody; Prion protein; Immunotherapy; Biology; Immunology; Computational biology; Immune system; Medicine; Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001578999,0.001177903,0.001978005,0.001810421,0.0003168849,0.001282095,0.0013467,0.002479945,0.003248541],"category_scores_gemma":[0.0007600217,0.0003681016,0.0004941014,0.001605018,0.0008524176,0.001915334,0.0007953388,0.002731343,0.004047215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001028085,"about_ca_system_score_gemma":0.0009360375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007773182,"about_ca_topic_score_gemma":0.0009448018,"domain_scores_codex":[0.9994972,0.0001081867,0.0000389624,0.00007763213,0.0002308121,0.00004720916],"domain_scores_gemma":[0.9996837,0.00013566,0.0000389091,0.00001721088,0.00008711199,0.00003745811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001067769,0.0001517386,0.0001136582,0.009252588,0.000064118,0.0003675181,0.00009064743,0.0007226407,0.01275228,0.01082087,0.02744682,0.9381104],"study_design_scores_gemma":[0.00004065112,0.0001490046,0.0003344864,0.001591321,0.00004227693,0.001040009,0.00004280515,0.0001693661,0.002413661,0.005297173,0.9888598,0.00001956513],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002074917,0.9967445,0.000617663,0.0005902334,0.0004262821,0.000008248037,0.00000889008,0.0000157652,0.001380999],"genre_scores_gemma":[0.001225932,0.9959573,0.000821172,0.0005090183,0.0003689031,0.00001809298,0.0000270494,0.00000376803,0.001068782],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003248541,"threshold_uncertainty_score":0.01086748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08530481527831522,"score_gpt":0.3998704850816071,"score_spread":0.3145656698032918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}