{"id":"W2111021925","doi":"10.1517/14712598.5.1.97","title":"Progress in prion vaccines and immunotherapies","year":2005,"lang":"en","type":"review","venue":"Expert Opinion on Biological Therapy","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Epitope; Gene isoform; Virology; Antibody; Prion protein; Immunotherapy; Biology; Immunology; Computational biology; Immune system; Medicine; Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001867461,0.0004083285,0.0006562108,0.00008448466,0.00006494495,0.00004173652,0.0002701171,0.0005552486,0.00008430104],"category_scores_gemma":[0.00002400593,0.000254348,0.000255809,0.00009973383,0.00008305573,0.000003230353,0.00009393818,0.0001735993,0.000008731897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002050694,"about_ca_system_score_gemma":0.00004182509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002264196,"about_ca_topic_score_gemma":3.99181e-7,"domain_scores_codex":[0.9984075,0.0002735056,0.0003680259,0.0006004528,0.00008509973,0.0002654478],"domain_scores_gemma":[0.9993968,0.00003795888,0.0001537326,0.0003212279,0.00001846018,0.00007183068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001490407,0.000111507,0.00005911328,0.00003395946,0.00005000517,0.000001070405,0.00001591338,8.770159e-8,0.00009519188,0.00005220737,0.0001713402,0.9992605],"study_design_scores_gemma":[0.0004972109,0.0006178199,0.0001569983,0.0009336605,3.929663e-7,0.000008824649,0.000008421446,6.305125e-7,0.00005973606,0.00002546062,0.9973394,0.0003514521],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005793734,0.9983052,0.000006051187,0.0001376505,0.0001893662,0.0007221614,0.00001294027,0.00002449499,0.00002273765],"genre_scores_gemma":[0.0002708972,0.9977088,0.0002009671,0.0004048773,0.0007707793,0.0003634809,0.0002364574,0.00003496859,0.000008764779],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9989091,"threshold_uncertainty_score":0.9999909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08530481527831522,"score_gpt":0.3998704850816071,"score_spread":0.3145656698032918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}