{"id":"W2111063079","doi":"10.1186/1477-5751-3-5","title":"CP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on p53 transcriptional activity","year":2004,"lang":"en","type":"article","venue":"Journal of Negative Results in BioMedicine","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Semtech (Canada)","funders":"","keywords":"Yeast; Chemistry; Saccharomyces cerevisiae; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009831933,0.0002782843,0.0007557894,0.001282631,0.00003148648,0.00001114828,0.00009554599,0.0001864796,0.000003665543],"category_scores_gemma":[0.001472095,0.0002287346,0.0001121936,0.001091343,0.0001836515,0.0001604738,0.0000185924,0.0008126145,0.000001880575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001038522,"about_ca_system_score_gemma":0.0003819027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000791382,"about_ca_topic_score_gemma":0.000192087,"domain_scores_codex":[0.9976657,0.0001786429,0.0008551913,0.0003651516,0.0005549366,0.0003803513],"domain_scores_gemma":[0.9983543,0.0006056163,0.0004302687,0.0001347273,0.0002520548,0.0002230321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01303426,0.0007617827,0.0001785798,0.0003184571,0.00007219304,0.001351162,0.003696127,0.0008220188,0.9748058,0.00004074321,0.00004282936,0.004876094],"study_design_scores_gemma":[0.07505924,0.007185549,0.1122972,0.007236328,0.0001001582,0.0003119936,0.0008406151,0.0005024225,0.795288,0.0006005356,0.0002852865,0.0002926143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917614,0.000580546,0.0006363302,0.005198557,0.0002687391,0.001245846,0.0001179167,0.000008986628,0.000181643],"genre_scores_gemma":[0.9976491,0.000142918,0.001617366,0.0003199499,0.0001720345,0.00002925964,0.00001456138,0.00003320725,0.00002162054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1795177,"threshold_uncertainty_score":0.9327527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02221842095401186,"score_gpt":0.2989796176630747,"score_spread":0.2767611967090628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}