{"id":"W2111072547","doi":"10.1002/bies.20089","title":"PML nuclear bodies: dynamic sensors of DNA damage and cellular stress","year":2004,"lang":"en","type":"review","venue":"BioEssays","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":393,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"DNA damage; DNA repair; Cell biology; Genome instability; Biology; Transcription factor; DNA; Promyelocytic leukemia protein; Genetics; Cancer research; Nuclear protein; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001588724,0.0004911487,0.0009542699,0.00009439735,0.00008557669,0.0000375567,0.0004305776,0.0007282684,0.00003265633],"category_scores_gemma":[0.00006227512,0.0004177135,0.0003387938,0.0001006943,0.0003550636,0.000003973582,0.0002874723,0.0002335381,0.00001666772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004332518,"about_ca_system_score_gemma":0.000274122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001378343,"about_ca_topic_score_gemma":0.000004015225,"domain_scores_codex":[0.9982043,0.0001131724,0.0005221067,0.0006553895,0.0001857517,0.0003192826],"domain_scores_gemma":[0.9987341,0.00002206079,0.0003935262,0.0006653111,0.00007645588,0.0001085879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001232715,0.0008252182,0.00005558026,0.4048642,0.002632353,0.0003999353,0.0006865712,0.00004847397,0.115839,0.002242791,0.00217126,0.4701114],"study_design_scores_gemma":[0.0003270186,0.000216774,0.000001327064,0.005990485,0.0005099055,0.0000460367,0.0001270393,0.000005925939,0.01172729,0.00006451066,0.9803204,0.0006633121],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006287323,0.9913689,0.00004080799,0.000007645775,0.0001618644,0.0003343268,0.0002321315,0.00002117553,0.001545765],"genre_scores_gemma":[0.004893707,0.9932024,0.0002775019,0.00001392717,0.0001297084,0.00001670165,0.0006080375,0.0001065118,0.0007514349],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9781491,"threshold_uncertainty_score":0.9998274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01160011711611387,"score_gpt":0.2667250125181178,"score_spread":0.2551248954020039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}