{"id":"W2111117232","doi":"10.1093/molbev/msr138","title":"A Comprehensive Study of Polymorphic Sites along the HLA-G Gene: Implication for Gene Regulation and Evolution","year":2011,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Biology; HLA-G; Human leukocyte antigen; Linkage disequilibrium; Untranslated region; Gene; Haplotype; Genetics; Balancing selection; Coding region; CIITA; Three prime untranslated region; Locus (genetics); Major histocompatibility complex; Gene expression; Regulatory sequence; Allele; Messenger RNA; Antigen; MHC class II","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002158734,0.0001295122,0.0001987749,0.00008406486,0.0002550545,0.000003253636,0.00007810805,0.0002044265,0.000007239542],"category_scores_gemma":[0.00004429179,0.00009699595,0.00004101031,0.00009828356,0.0002609117,0.00005267825,0.00005428724,0.00007532309,0.000004385782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002084972,"about_ca_system_score_gemma":0.00001867949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005556316,"about_ca_topic_score_gemma":0.00003029538,"domain_scores_codex":[0.9988045,0.0003829398,0.0002597345,0.0003674799,0.00001807101,0.000167248],"domain_scores_gemma":[0.9992909,0.00005310228,0.0001869815,0.0002905897,0.0001665913,0.00001184285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001324031,0.00008017312,0.1400646,0.00001988259,0.0001299462,2.032737e-7,0.0007962368,0.000002925379,0.851117,0.007201636,0.00001840155,0.0004365438],"study_design_scores_gemma":[0.000899697,0.0007017534,0.8782169,0.00001156732,0.0001008578,0.00007050086,0.0004580108,0.00001253791,0.1122305,0.007155355,0.00003853286,0.0001038014],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9494447,0.02610102,0.02319751,0.00006025341,0.0001642454,0.0009606133,0.00001973177,0.00002090277,0.00003106038],"genre_scores_gemma":[0.9994473,0.00003423652,0.000207658,0.00001204094,0.00002439092,0.0001151006,0.0001134952,0.000008216665,0.00003759935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7388865,"threshold_uncertainty_score":0.395538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02264114181349941,"score_gpt":0.2577928755560496,"score_spread":0.2351517337425502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}