{"id":"W2111117232","doi":"10.1093/molbev/msr138","title":"A Comprehensive Study of Polymorphic Sites along the HLA-G Gene: Implication for Gene Regulation and Evolution","year":2011,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Biology; HLA-G; Human leukocyte antigen; Linkage disequilibrium; Untranslated region; Gene; Haplotype; Genetics; Balancing selection; Coding region; CIITA; Three prime untranslated region; Locus (genetics); Major histocompatibility complex; Gene expression; Regulatory sequence; Allele; Messenger RNA; Antigen; MHC class II","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392031,0.0002018652,0.0003336024,0.000814073,0.0002159904,0.0001822383,0.0001465943,0.000162257,0.001143657],"category_scores_gemma":[0.0003459809,0.00007034632,0.0003242339,0.001530902,0.0001561164,0.0001104891,0.0002268402,0.0001792536,0.0002065337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001066475,"about_ca_system_score_gemma":0.0002486444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001655976,"about_ca_topic_score_gemma":0.002773878,"domain_scores_codex":[0.9998469,0.00003259776,0.00001125499,0.0000615093,0.00002794437,0.00001989154],"domain_scores_gemma":[0.9997382,0.0000655838,0.0000900959,0.00002964379,0.00003126682,0.00004527512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000424061,0.00008680057,0.3530529,0.0004705688,0.0003095653,0.001406253,0.0006651677,0.0007532606,0.5223791,0.0004416759,0.0002173091,0.1197933],"study_design_scores_gemma":[0.00001388621,0.00025251,0.9815639,0.00004965261,0.0001706033,0.002513441,0.0001489268,0.0003754889,0.007062839,0.0002499774,0.007586941,0.00001180654],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902232,0.004618066,0.002810933,0.00004872568,0.000006128971,0.00002557384,0.001001831,0.00001639072,0.001249133],"genre_scores_gemma":[0.9902695,0.003096903,0.00415055,0.00005435535,0.00001342896,0.00002105042,0.001790503,0.000009336924,0.0005942874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001655976,"threshold_uncertainty_score":0.003825963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02264114181349941,"score_gpt":0.2577928755560496,"score_spread":0.2351517337425502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}