{"id":"W2111254733","doi":"10.1046/j.1359-4117.2003.01075.x","title":"Combined treatment of Bcl‐2 antisense oligodeoxynucleotides (G3139), p‐glycoprotein inhibitor (PSC833), and sterically stabilized liposomal doxorubicin suppresses growth of drug‐resistant growth of drug‐resistant breast cancer in severely combined immunodeficient mice","year":2003,"lang":"en","type":"article","venue":"Journal of Experimental Therapeutics and Oncology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Celator Pharmaceuticals (Canada); University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute","keywords":"Drug; Doxorubicin; Liposome; P-glycoprotein; Chemistry; Drug resistance; Breast cancer; Pharmacology; Cancer research; Cancer; Multiple drug resistance; Chemotherapy; Medicine; Biochemistry; Biology; Internal medicine; Microbiology; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242806,0.0004181273,0.0003941671,0.0002606162,0.0001079498,0.0001695053,0.0002171418,0.0002856426,0.0006376283],"category_scores_gemma":[0.00008223804,0.0001672537,0.0002040548,0.0001624491,0.0002063788,0.0001739865,0.0001377938,0.0006239575,0.0002143295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001904269,"about_ca_system_score_gemma":0.0002745884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005653743,"about_ca_topic_score_gemma":0.0013545,"domain_scores_codex":[0.9998623,0.00002207114,0.00001385562,0.00002978353,0.00003404563,0.00003793681],"domain_scores_gemma":[0.9999179,0.00001189791,0.00002240192,0.00001078411,0.000006232635,0.00003087785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002407751,0.0001052458,0.0001020461,0.00001760306,0.000005754336,0.00002879804,0.000008713143,0.00007774225,0.9982018,0.00003970269,0.00003149271,0.001140369],"study_design_scores_gemma":[0.0001102581,0.002090583,0.001558618,0.000002837073,0.0000257685,0.0001438941,0.000007132597,0.0008190348,0.9944155,0.00002165065,0.0008002393,0.000004503718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980173,0.0005303089,0.0006217441,0.00005896016,0.00002712013,0.00003412333,0.0001218302,0.00007408644,0.0005145376],"genre_scores_gemma":[0.9969864,0.0005245305,0.001207452,0.00004515885,0.0000141732,0.00004722152,0.0002277102,0.00001059922,0.0009367266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006376283,"threshold_uncertainty_score":0.002133071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01375766376512696,"score_gpt":0.2769492816888141,"score_spread":0.2631916179236871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}