{"id":"W2111257615","doi":"10.1086/644768","title":"Trends in Multidrug Treatment Failure and Subsequent Mortality among Antiretroviral Therapy–Experienced Patients with HIV Infection in North America","year":2009,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University; University of Calgary; Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Drug Abuse; U.S. Public Health Service; National Cancer Institute; National Institutes of Health","keywords":"Medicine; Regimen; Internal medicine; Proportional hazards model; Viral load; Mortality rate; Antiretroviral therapy; Immunology; Human immunodeficiency virus (HIV)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005083789,0.0001453083,0.000171385,0.0007353475,0.0003717687,0.0005273766,0.0003508317,0.0004098458,0.001284441],"category_scores_gemma":[0.001230547,0.000173655,0.0002221569,0.0009236341,0.0002388032,0.00051057,0.0003136257,0.0004446946,0.0001509095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006674042,"about_ca_system_score_gemma":0.0005053624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03338255,"about_ca_topic_score_gemma":0.04164359,"domain_scores_codex":[0.9996988,0.00007641854,0.00002958301,0.00007188894,0.00006857389,0.00005490145],"domain_scores_gemma":[0.9985746,0.000181358,0.0007090782,0.0000476712,0.0002445156,0.0002426738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000145888,0.000009983138,0.9990889,0.000003870006,0.00001347413,0.0000163427,0.00004541179,0.00002902588,0.00003608985,0.000007995967,0.0001409275,0.0005934493],"study_design_scores_gemma":[0.000002416454,0.00001654553,0.9994273,0.000006853568,0.000007801378,0.00007037939,0.0001296793,0.0001631012,0.00001462314,0.000007746589,0.0001520407,0.000001477149],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984812,0.0003885937,0.00004052482,0.0001598901,0.00000523201,0.000004580397,0.0004576134,0.000005385099,0.0004569697],"genre_scores_gemma":[0.9989446,0.0002187335,0.00006411157,0.00005339748,0.00001256418,0.000007957472,0.0005749995,0.000001391198,0.0001221236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03338255,"threshold_uncertainty_score":0.06637651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02073094666257519,"score_gpt":0.3231218992976396,"score_spread":0.3023909526350644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}