{"id":"W2111274962","doi":"10.2174/156652306775515592","title":"RNA Based Gene Therapy for Dominantly Inherited Diseases","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Genetic enhancement; RNA; Genetics; Gene; Biology; Computational biology; Medicine; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005375671,0.001000292,0.0011614,0.002000666,0.000311879,0.0006122187,0.001061438,0.001345578,0.003172463],"category_scores_gemma":[0.0003390667,0.0002901678,0.0003882491,0.001500966,0.0006343884,0.0009538821,0.0004476385,0.001598275,0.003523926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005610941,"about_ca_system_score_gemma":0.0004439976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005736183,"about_ca_topic_score_gemma":0.0008141793,"domain_scores_codex":[0.9997857,0.00003252242,0.00002036026,0.00003638034,0.0001056006,0.00001940277],"domain_scores_gemma":[0.9998741,0.00006658234,0.0000175707,0.000006605659,0.00002336342,0.00001177218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007285811,0.0001631874,0.0001194503,0.006844961,0.0000550346,0.0006927701,0.00009734461,0.0008374673,0.01872725,0.008150425,0.01988206,0.9443571],"study_design_scores_gemma":[0.00002964697,0.0001529819,0.0004989294,0.0008323406,0.00004640979,0.003332658,0.0000315307,0.0002023954,0.006102032,0.002752019,0.9859949,0.00002410773],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004982955,0.9916623,0.002376314,0.0002301531,0.0003109511,0.0000214811,0.00001748919,0.00004867852,0.004834319],"genre_scores_gemma":[0.002372156,0.9914393,0.001720176,0.0002900278,0.0001777372,0.0000292056,0.00004173523,0.000008765953,0.003920818],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003172463,"threshold_uncertainty_score":0.01061291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06942449154776023,"score_gpt":0.3622432113396636,"score_spread":0.2928187197919034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}