{"id":"W2111274962","doi":"10.2174/156652306775515592","title":"RNA Based Gene Therapy for Dominantly Inherited Diseases","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Genetic enhancement; RNA; Genetics; Gene; Biology; Computational biology; Medicine; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001610873,0.0008506022,0.001242183,0.0001676823,0.0001487542,0.00008381387,0.000750868,0.0004409793,0.00005028561],"category_scores_gemma":[0.00001806676,0.000667741,0.001378846,0.0001961167,0.0001073151,0.000005642019,0.00006411473,0.0001897891,0.00002943723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000441105,"about_ca_system_score_gemma":0.0005402213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009038785,"about_ca_topic_score_gemma":0.000003125901,"domain_scores_codex":[0.9973062,0.0001956938,0.000708919,0.001000762,0.0002145331,0.0005738995],"domain_scores_gemma":[0.9981915,0.00004557089,0.0004369501,0.000965772,0.000205368,0.0001548213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002936752,0.0004023315,0.00001131042,0.0007791633,0.0002788513,0.000002505568,0.000004690909,0.000005937355,0.0100775,0.000001859877,0.01609108,0.9720511],"study_design_scores_gemma":[0.001667435,0.0007501947,0.0000167212,0.0006981426,0.0001708872,0.00000583527,0.000001416433,0.00001418788,0.02135983,0.00002305412,0.9744616,0.0008307414],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005055615,0.9886857,0.001784049,0.00001555029,0.001218792,0.001891795,0.001282828,0.00004024699,0.00002543262],"genre_scores_gemma":[0.000223932,0.985949,0.0002569489,0.0001753525,0.002030607,0.001046822,0.009837418,0.0001626463,0.0003173039],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9712204,"threshold_uncertainty_score":0.9995774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06942449154776023,"score_gpt":0.3622432113396636,"score_spread":0.2928187197919034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}