{"id":"W2111335317","doi":"10.1093/neuonc/nou091","title":"Phase 2 study of safety and efficacy of nimotuzumab in pediatric patients with progressive diffuse intrinsic pontine glioma","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Toronto","funders":"","keywords":"Nimotuzumab; Medicine; Adverse effect; Internal medicine; Clinical trial; Phases of clinical research; Radiation therapy; Oncology; Glioma; Surgery; Epidermal growth factor receptor; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001238104,0.001098975,0.001422942,0.0002121987,0.0002122234,0.0004032746,0.0005336949,0.0005372024,0.001497278],"category_scores_gemma":[0.001001239,0.0002525823,0.0005341445,0.0002685154,0.0005013343,0.0004216891,0.0002909248,0.001841552,0.0003234109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009076089,"about_ca_system_score_gemma":0.001679377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006883066,"about_ca_topic_score_gemma":0.001317048,"domain_scores_codex":[0.9996094,0.000221547,0.00002078103,0.00005384501,0.00004020965,0.00005438286],"domain_scores_gemma":[0.9993249,0.0001299815,0.000197962,0.00004658385,0.00004103943,0.0002596244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5104414,0.06421933,0.07742827,0.001281097,0.002039378,0.002693772,0.001139123,0.006470114,0.07926232,0.0006783477,0.006669783,0.247677],"study_design_scores_gemma":[0.2860667,0.6232496,0.06471872,0.00006746496,0.0005575648,0.002980908,0.0001144185,0.002793028,0.01121302,0.0002473023,0.007962665,0.00002859513],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968958,0.001171123,0.00037687,0.000122167,0.00001767173,0.0006314903,0.0002795244,0.00003476232,0.0004706247],"genre_scores_gemma":[0.993596,0.001094558,0.001848423,0.0002449273,0.00006583847,0.00123433,0.001400225,0.00001950546,0.0004961506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001497278,"threshold_uncertainty_score":0.00658524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00936498273563688,"score_gpt":0.2840825631903334,"score_spread":0.2747175804546965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}