{"id":"W2111344235","doi":"10.1016/s0008-6363(01)00560-0","title":"Pyruvate dehydrogenase and the regulation of glucose oxidation in hypertrophied rat hearts","year":2002,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; Fondation pour la Recherche Médicale; National Institute of General Medical Sciences; Heart and Stroke Foundation of Canada","keywords":"Glycolysis; Internal medicine; Endocrinology; Glucose uptake; Pyruvate dehydrogenase complex; Coupling (piping); Chemistry; Dehydrogenase; Biology; Metabolism; Biochemistry; Enzyme; Medicine; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001713282,0.00007148157,0.0001792863,0.0001025775,0.00008200781,0.00001462691,0.00008842073,0.0001107637,0.00003863948],"category_scores_gemma":[0.0003960743,0.00005373286,0.0001673367,0.0002294798,0.0002958202,0.000004370786,0.00008120356,0.0001305389,0.00001461886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001026911,"about_ca_system_score_gemma":0.00001494675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004464614,"about_ca_topic_score_gemma":0.00001842584,"domain_scores_codex":[0.9982649,0.0008497256,0.0001653528,0.0002603867,0.0002764254,0.0001831881],"domain_scores_gemma":[0.9992555,0.00004148635,0.00002183085,0.0004999877,0.0001377139,0.00004342229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002575048,0.00002453553,0.0002321358,0.00001784806,0.00008594319,0.00000568419,0.00009750693,0.0003290394,0.9922317,0.0003869307,0.0007674052,0.005563762],"study_design_scores_gemma":[0.004640535,0.000176045,0.001889283,0.00001701106,0.00003265382,0.0000733225,0.00009131983,0.001452647,0.9108186,0.000355829,0.0803124,0.0001403762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854321,0.0125327,0.0004180697,0.0002453497,0.00009975876,0.0003955406,0.000001284927,0.000003878118,0.0008713611],"genre_scores_gemma":[0.9969437,0.002269954,0.0001099784,0.00003605813,0.0001462128,0.00004197291,0.0000234661,0.00001092312,0.000417707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08141313,"threshold_uncertainty_score":0.2191163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04296719332295689,"score_gpt":0.2750835040721642,"score_spread":0.2321163107492073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}