{"id":"W2111374186","doi":"10.4049/jimmunol.192.supp.45.9","title":"Differential contributions for Bim and Nur77 in negative selection against ubiquitous and tissue-restricted self-antigens (BA2P.122)","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Nerve growth factor IB; Biology; Clonal deletion; Transgene; Thymocyte; Negative selection; T-cell receptor; Cell biology; Genetically modified mouse; Major histocompatibility complex; Phenotype; Antigen; Genetics; Transcription factor; CD8; T cell; Immune system; Gene; Nuclear receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002188882,0.00008768807,0.0002087334,0.0001309081,0.0002199709,0.00002754901,0.0001150081,0.0000759184,0.00001400386],"category_scores_gemma":[0.0005708096,0.00005968479,0.00002775033,0.000147195,0.0001326141,0.00008661644,0.00003846902,0.0002692017,0.000002016443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003459074,"about_ca_system_score_gemma":0.00002665896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001982571,"about_ca_topic_score_gemma":0.00001170213,"domain_scores_codex":[0.9990062,0.000370915,0.000262687,0.00009458845,0.00007244368,0.0001931762],"domain_scores_gemma":[0.998907,0.0006823146,0.0002327565,0.00005743415,0.00008791891,0.00003258067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002342912,0.00007153252,0.0001250522,0.000003638962,0.0000207319,0.000001055759,0.0004903904,0.00001428506,0.9930654,0.001241535,0.00006340993,0.004668688],"study_design_scores_gemma":[0.00630226,0.00234794,0.02222448,0.00006725932,0.000109031,0.0005971905,0.0003891381,0.005578726,0.9512658,0.005341403,0.005545603,0.000231221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956086,0.0001955059,0.003110574,0.000512185,0.0003547412,0.0001666073,0.000005168714,0.00001290883,0.00003374577],"genre_scores_gemma":[0.9988168,0.0007972546,0.0001355651,0.0000859085,0.0001318401,0.000001785913,3.796117e-7,0.000009539494,0.00002085908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04179964,"threshold_uncertainty_score":0.2433875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032300045028819,"score_gpt":0.2548655805886654,"score_spread":0.2445425801383772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}