{"id":"W2111382211","doi":"10.1158/1078-0432.ccr-05-2703","title":"Association of DNA Repair and Steroid Metabolism Gene Polymorphisms with Clinical Late Toxicity in Patients Treated with Conformal Radiotherapy for Prostate Cancer","year":2006,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":141,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Prostate cancer; Internal medicine; Oncology; XRCC3; Medicine; Single-nucleotide polymorphism; Biology; Cancer research; Cancer; Urology; Genotype; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002170101,0.0002085514,0.000904424,0.0001405531,0.00007957272,0.00002490148,0.00008297053,0.0002033112,0.00004528744],"category_scores_gemma":[0.0001298954,0.0001358906,0.0001425831,0.0003747562,0.0003740301,0.0001263808,0.00003671622,0.0004416748,7.222175e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005315078,"about_ca_system_score_gemma":0.0006227472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003326924,"about_ca_topic_score_gemma":0.002238066,"domain_scores_codex":[0.9968361,0.0003084546,0.00101197,0.0005781529,0.0006817243,0.0005835656],"domain_scores_gemma":[0.9975774,0.0007097407,0.0003619805,0.0002932624,0.0008345104,0.000223163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01535032,0.001326506,0.9661514,0.00008440205,0.0005577508,0.00001251152,0.00007718074,0.00002198652,0.0001100435,0.00001297245,0.001179751,0.01511517],"study_design_scores_gemma":[0.02642196,0.006080968,0.9592245,0.0002679322,0.000191181,6.329974e-7,0.00001023163,0.0002031181,0.003997671,0.00001894772,0.003432146,0.00015074],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923274,0.002755627,0.000005673803,0.001706923,0.00008642425,0.002665878,0.0003644004,0.00003022604,0.00005747712],"genre_scores_gemma":[0.9887398,0.007728025,0.000474278,0.0003300516,0.0002829935,0.001089197,0.00009798697,0.00004691222,0.001210683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01496443,"threshold_uncertainty_score":0.5541456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06221923651045298,"score_gpt":0.4224770252036543,"score_spread":0.3602577886932014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}