{"id":"W2111418333","doi":"10.1128/iai.72.3.1223-1229.2004","title":"Role of MyD88 in Diminished Tumor Necrosis Factor Alpha Production by Newborn Mononuclear Cells in Response to Lipopolysaccharide","year":2004,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; IWK Health Centre; Sick Kids Foundation","keywords":"Tumor necrosis factor alpha; CD14; Peripheral blood mononuclear cell; Lipopolysaccharide; Biology; Secretion; Internal medicine; Endocrinology; Cytokine; Immunology; Immune system; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004257502,0.0002415557,0.0003289422,0.0001418204,0.0001044707,0.0002851801,0.0002059636,0.0002629343,0.0007513314],"category_scores_gemma":[0.0005384699,0.0001147563,0.0001527166,0.00007009801,0.0002364648,0.0001180458,0.0003183791,0.0003045053,0.0002532261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002177121,"about_ca_system_score_gemma":0.0001871298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002148502,"about_ca_topic_score_gemma":0.0001731316,"domain_scores_codex":[0.9997383,0.00009509021,0.00003573778,0.00003663859,0.00005233796,0.0000418736],"domain_scores_gemma":[0.999719,0.00003962683,0.00009512719,0.00002691294,0.00002701039,0.00009233216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001517868,0.00004586004,0.005992949,0.0001476413,0.00001273969,0.0007975189,0.0001536631,0.00003257179,0.9855464,0.0001004217,0.00006858452,0.005583877],"study_design_scores_gemma":[0.000140006,0.004212371,0.3211487,0.0001654661,0.0001322435,0.008678568,0.0006810258,0.0009696754,0.6573958,0.0001765307,0.006280498,0.00001910272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956428,0.003134569,0.0005940472,0.00007811908,0.00001670076,0.00002014404,0.00009824694,0.00001260643,0.000402766],"genre_scores_gemma":[0.9969518,0.001146413,0.0008798391,0.0001029282,0.00001748293,0.00005187322,0.0001669986,0.000006124455,0.0006766088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007513314,"threshold_uncertainty_score":0.002513409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006552624152650698,"score_gpt":0.2238944004802545,"score_spread":0.2173417763276038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}