{"id":"W2111479968","doi":"10.1200/jco.2006.06.7835","title":"Elderly Patients Benefit From Second-Line Cytotoxic Chemotherapy: A Subset Analysis of a Randomized Phase III Trial of Pemetrexed Compared With Docetaxel in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Eli Lilly and Company","keywords":"Docetaxel; Pemetrexed; Medicine; Tolerability; Internal medicine; Neutropenia; Chemotherapy; Lung cancer; Oncology; Febrile neutropenia; Population; Toxicity; Surgery; Adverse effect; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002098354,0.0007642327,0.00181444,0.0002169739,0.0002286244,0.0007234114,0.0004343282,0.0005316237,0.00138782],"category_scores_gemma":[0.001928241,0.0003296369,0.002128016,0.000243285,0.0004492709,0.0004167222,0.0002736828,0.00105714,0.0001781053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000476823,"about_ca_system_score_gemma":0.0006040757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003468915,"about_ca_topic_score_gemma":0.001225384,"domain_scores_codex":[0.9992458,0.0004902167,0.00005941743,0.00008434722,0.00004901992,0.00007115996],"domain_scores_gemma":[0.9986941,0.00039145,0.0004424416,0.0001146866,0.00005077373,0.0003066124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9485697,0.003819818,0.01964691,0.0003171444,0.004288614,0.0001368539,0.00009688312,0.001001994,0.004681637,0.00006204707,0.0006937736,0.01668465],"study_design_scores_gemma":[0.7342314,0.1720859,0.07968645,0.00007801448,0.006919377,0.0004202832,0.0001172532,0.002195444,0.002195262,0.0002396385,0.001786303,0.00004471322],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975569,0.001458752,0.0001304084,0.0000992375,0.00003635959,0.0002671869,0.0002167439,0.00000792587,0.0002264153],"genre_scores_gemma":[0.9976664,0.0006423324,0.0002746151,0.0002449819,0.00007293362,0.0003085103,0.0005293199,0.000004461309,0.0002564816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002098354,"threshold_uncertainty_score":0.01109725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02282379912447964,"score_gpt":0.3976881623197988,"score_spread":0.3748643631953192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}