{"id":"W2111488265","doi":"10.1158/1078-0432.ccr-14-2497","title":"Germline Mutation in <i>BRCA1</i> or <i>BRCA2</i> and Ten-Year Survival for Women Diagnosed with Epithelial Ovarian Cancer","year":2014,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Lunenfeld-Tanenbaum Research Institute","funders":"National Cancer Institute; Cancer Research UK; Francis Crick Institute","keywords":"Germline; Ovarian cancer; Germline mutation; Cancer; Epithelial ovarian cancer; Gynecology; Medicine; Oncology; Mutation; Internal medicine; Cancer research; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003335543,0.0001824799,0.0003358944,0.0001005288,0.0001471578,0.0000613563,0.0002907952,0.0002627991,0.0001142368],"category_scores_gemma":[0.001207594,0.0001430532,0.00005747227,0.0003576915,0.0004959491,0.00001156254,0.0001498224,0.0003923881,0.000005341834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002211948,"about_ca_system_score_gemma":0.001198297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005211048,"about_ca_topic_score_gemma":0.009149073,"domain_scores_codex":[0.9972287,0.000474027,0.0004846273,0.0007902108,0.0003795936,0.0006428133],"domain_scores_gemma":[0.9980741,0.0007095778,0.0001029825,0.0004279976,0.0004637882,0.0002216287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03849114,0.001657754,0.4574209,0.0009077625,0.0008916535,0.00007149768,0.002319937,0.003178796,0.0413725,0.001005469,0.02729303,0.4253895],"study_design_scores_gemma":[0.04333768,0.01041154,0.261469,0.0003865446,0.00009138709,0.00001747468,0.00213935,0.002204299,0.03200483,0.002574053,0.6437293,0.001634574],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939646,0.0005831913,0.001125877,0.002382823,0.0004135062,0.0009236474,0.0001976228,0.00001487245,0.0003938822],"genre_scores_gemma":[0.9898329,0.002081589,0.001080752,0.0006561333,0.001785286,0.002497213,0.00006433298,0.00006684485,0.001934974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6164362,"threshold_uncertainty_score":0.5833541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08217853277080826,"score_gpt":0.4480162240044228,"score_spread":0.3658376912336145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}