{"id":"W2111489144","doi":"10.1158/0008-5472.can-05-4411","title":"Highly Efficacious Nontoxic Preclinical Treatment for Advanced Metastatic Breast Cancer Using Combination Oral UFT-Cyclophosphamide Metronomic Chemotherapy","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Cancer Institute","keywords":"Medicine; Cyclophosphamide; Chemotherapy; Metastatic breast cancer; Combination therapy; Pharmacology; Breast cancer; Prodrug; Cancer; Oncology; Combination chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004622854,0.0002432777,0.0003316119,0.00009499618,0.0002365397,0.00004962275,0.0002377819,0.0001340701,0.0001033175],"category_scores_gemma":[0.00002098093,0.0002132265,0.0002343219,0.0002134649,0.0001757848,0.00001141907,0.00005206532,0.00009524258,0.000004835512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007041081,"about_ca_system_score_gemma":0.0005812064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001814015,"about_ca_topic_score_gemma":0.0009609784,"domain_scores_codex":[0.9979796,0.0001348496,0.000348111,0.0006456749,0.0002672805,0.0006244508],"domain_scores_gemma":[0.9989752,0.00007768632,0.0001158546,0.0003705781,0.0003440716,0.000116564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002563549,0.0007251611,0.00881773,0.00007904753,0.000460094,0.000002970747,0.00003656145,0.006807541,0.8869817,0.0001493053,0.004157401,0.08921888],"study_design_scores_gemma":[0.01299389,0.001607897,0.01976827,0.0001111611,0.0001788768,0.00001170266,0.00008386836,0.002511242,0.8851198,0.0004092871,0.0764384,0.0007656047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855093,0.01031994,0.001678652,0.0007313107,0.0002876158,0.001041086,0.000348806,0.00001742321,0.00006588513],"genre_scores_gemma":[0.991507,0.00289806,0.001465317,0.0001171836,0.0006396116,0.001180976,0.0001423435,0.00007756197,0.001971937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08845328,"threshold_uncertainty_score":0.8695125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07068284038228259,"score_gpt":0.4304638379663733,"score_spread":0.3597809975840907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}