{"id":"W2111490248","doi":"10.1210/me.2003-0025","title":"RFX1 and NF-1 Associate with P Sequences of the Human Growth Hormone Locus in Pituitary Chromatin","year":2003,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Chromatin immunoprecipitation; Biology; Molecular biology; Promoter; Chromatin; Immunoprecipitation; Locus (genetics); Histone; Repressor; Transcription factor; Transfection; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001757253,0.0003652345,0.0001263017,0.0002398613,0.0003252066,0.0003491249,0.0002084325,0.0002712992,0.002577045],"category_scores_gemma":[0.000301098,0.000298645,0.0003219592,0.0001511382,0.0003414478,0.0003194611,0.0004693989,0.0003771519,0.001243256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004339505,"about_ca_system_score_gemma":0.0001919623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007939171,"about_ca_topic_score_gemma":0.0009676591,"domain_scores_codex":[0.9998115,0.0000199016,0.000007978746,0.00007036711,0.00005042141,0.00003991329],"domain_scores_gemma":[0.999762,0.00004215451,0.00007078178,0.00002375141,0.00001886345,0.00008252461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002083607,0.00002992317,0.002616558,0.00005187996,0.00001177602,0.0001041246,0.00009654712,0.00005100871,0.9943704,0.0002130883,0.00007429796,0.002172],"study_design_scores_gemma":[0.0001162269,0.0006436704,0.1982048,0.00004986393,0.00003542464,0.001970034,0.0002835789,0.001404269,0.7864894,0.000934926,0.009842364,0.0000253281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909213,0.003065122,0.003582904,0.0001163379,0.0000263258,0.00001909022,0.0001589997,0.00006805644,0.002041896],"genre_scores_gemma":[0.9882928,0.001033703,0.002396289,0.0001121859,0.00004881451,0.00004608632,0.001327608,0.00002998708,0.006712632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002577045,"threshold_uncertainty_score":0.008621037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005987861878787572,"score_gpt":0.2373935833788326,"score_spread":0.231405721500045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}