{"id":"W2111490248","doi":"10.1210/me.2003-0025","title":"RFX1 and NF-1 Associate with P Sequences of the Human Growth Hormone Locus in Pituitary Chromatin","year":2003,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Chromatin immunoprecipitation; Biology; Molecular biology; Promoter; Chromatin; Immunoprecipitation; Locus (genetics); Histone; Repressor; Transcription factor; Transfection; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001723386,0.0002097563,0.0002546818,0.0001039704,0.00008383096,0.00001259901,0.000297239,0.000169366,0.00001392638],"category_scores_gemma":[0.0001296483,0.0001672484,0.00007570429,0.0002435141,0.0003411718,0.000004483469,0.0001900682,0.0002813093,0.000002092021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004310928,"about_ca_system_score_gemma":0.0001402662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002236817,"about_ca_topic_score_gemma":0.0002278834,"domain_scores_codex":[0.9981605,0.0003698243,0.0002633442,0.0004509508,0.0002415667,0.0005137994],"domain_scores_gemma":[0.9992615,0.00001329017,0.0001211604,0.0004417979,0.00009731855,0.00006493831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002927001,0.00005430284,0.001041037,0.00001937186,0.00007699247,0.0001116062,0.00003510357,0.00008996174,0.9943156,0.003983272,0.00005756104,0.0001858866],"study_design_scores_gemma":[0.001298797,0.0005400443,0.002445164,0.00002087643,0.00002486615,0.0002093414,0.00006392802,0.000006533873,0.9934203,0.001188179,0.0005851517,0.0001968286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920134,0.003984472,0.001591192,0.0002461546,0.00004238857,0.0003521868,0.00000941175,0.000009989987,0.0017508],"genre_scores_gemma":[0.9989431,0.0002247396,0.0004217403,0.0001831418,0.00001318143,0.00005516069,0.00001391142,0.00003429258,0.0001107459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006929682,"threshold_uncertainty_score":0.6820191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005987861878787572,"score_gpt":0.2373935833788326,"score_spread":0.231405721500045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}