{"id":"W2111503808","doi":"10.1021/ja510963k","title":"Boron-Containing Enamine and Enamide Linchpins in the Synthesis of Nitrogen Heterocycles","year":2014,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Enamine; Annulation; Regioselectivity; Combinatorial chemistry; Amination; Boron; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001824285,0.0002918416,0.0001677045,0.0002437726,0.0001430064,0.000157221,0.0002258509,0.0002214227,0.001145815],"category_scores_gemma":[0.00009675001,0.00009687769,0.0001266075,0.00019836,0.0002001449,0.0002332014,0.0002096117,0.0002227587,0.0005064397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285023,"about_ca_system_score_gemma":0.0001972373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004790535,"about_ca_topic_score_gemma":0.001426221,"domain_scores_codex":[0.9998904,0.00002249937,0.00001008959,0.00002370467,0.00002488292,0.0000282744],"domain_scores_gemma":[0.9999468,0.000008246524,0.00001491818,0.000006745576,0.000006652152,0.00001655195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001283463,0.00005924125,0.0001851193,0.0001562592,0.000009434617,0.0002423272,0.00006897299,0.000605951,0.9816718,0.001914975,0.000145757,0.01481171],"study_design_scores_gemma":[0.00003183065,0.0006760596,0.000895139,0.00001728653,0.00001472789,0.0003664544,0.00001849291,0.0007632239,0.9834031,0.0001612641,0.01363706,0.00001518891],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9347017,0.008557514,0.02549792,0.0001692347,0.00008603101,0.0001680712,0.0004216324,0.0002237804,0.03017403],"genre_scores_gemma":[0.9730476,0.003497549,0.01704923,0.00006477419,0.0000206561,0.00006406663,0.0002415084,0.00003032751,0.005984352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001145815,"threshold_uncertainty_score":0.003833115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01204902140640602,"score_gpt":0.2657453714672256,"score_spread":0.2536963500608196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}