{"id":"W2111583269","doi":"10.1371/journal.pone.0034942","title":"Axin1 Prevents Salmonella Invasiveness and Inflammatory Response in Intestinal Epithelial Cells","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; U.S. Department of Defense; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; American Cancer Society","keywords":"AXIN2; SUMO protein; Wnt signaling pathway; Biology; Inflammation; Salmonella; Microbiology; Cell biology; Immunology; Signal transduction; Bacteria; Genetics; Ubiquitin; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001834801,0.0002831824,0.0002550018,0.0001786203,0.000134734,0.0001560676,0.0001704416,0.0002257304,0.002204207],"category_scores_gemma":[0.0001449153,0.000119383,0.0001838489,0.0001057985,0.000219114,0.0001227072,0.0001848249,0.0005258291,0.0003140521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002638705,"about_ca_system_score_gemma":0.0003761128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003612038,"about_ca_topic_score_gemma":0.0007658417,"domain_scores_codex":[0.9998982,0.0000177509,0.000008980101,0.00001735538,0.00002649981,0.00003129184],"domain_scores_gemma":[0.9998952,0.0000175799,0.00002205159,0.00001549476,0.00001081929,0.00003882055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004577693,0.00008720729,0.000225508,0.0001050118,0.000006042981,0.00004285947,0.00001365223,0.00006007158,0.9970793,0.0000878678,0.0001128258,0.001721966],"study_design_scores_gemma":[0.00005953557,0.001005441,0.004302045,0.00001222747,0.00001559414,0.0002175975,0.00004125045,0.0006130256,0.99058,0.00005627063,0.003093215,0.000003800769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938356,0.002644382,0.001084559,0.0001608789,0.00006024893,0.00002751834,0.000300755,0.0001114191,0.001774482],"genre_scores_gemma":[0.9937703,0.001091606,0.001094945,0.0000723359,0.00001079566,0.00004120986,0.0004602418,0.00001471614,0.003443823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002204207,"threshold_uncertainty_score":0.00737381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433362463428681,"score_gpt":0.2254033636748779,"score_spread":0.2010697390405911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}