{"id":"W2111585639","doi":"10.1111/j.1365-2036.2006.03088.x","title":"Oral V<sub>2</sub> receptor antagonist (RWJ‐351647) in patients with cirrhosis and ascites: a randomized, double‐blind, placebo‐controlled, single ascending dose study","year":2006,"lang":"en","type":"article","venue":"Alimentary Pharmacology & Therapeutics","topic":"Electrolyte and hormonal disorders","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Cirrhosis; Tolerability; Internal medicine; Ascites; Gastroenterology; Furosemide; Free water clearance; Placebo; Diuretic; Urine osmolality; Concomitant; Vasopressin; Pharmacokinetics; Endocrinology; Pharmacology; Adverse effect; Urology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009643605,0.0009854838,0.003023973,0.000399591,0.0003453782,0.0006211743,0.0005155231,0.001208782,0.003064812],"category_scores_gemma":[0.0007092623,0.0005555366,0.001024581,0.0003496562,0.0008362051,0.0006483958,0.0002396258,0.001287901,0.0006028472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002896299,"about_ca_system_score_gemma":0.0008827392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004098178,"about_ca_topic_score_gemma":0.0007167322,"domain_scores_codex":[0.9996629,0.0001506304,0.00003541218,0.00005775399,0.00003646889,0.00005689218],"domain_scores_gemma":[0.9994326,0.0001191222,0.0001282274,0.0000392632,0.00004868072,0.0002320174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9309847,0.0149472,0.001861046,0.001217622,0.0011343,0.0001284119,0.00007715932,0.0003345335,0.02133825,0.00007290042,0.0005458646,0.02735782],"study_design_scores_gemma":[0.7538488,0.2376531,0.005474489,0.00003168467,0.000521437,0.00008877384,0.00002906975,0.000384611,0.001240776,0.00004736632,0.0006574739,0.00002241936],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938531,0.003762963,0.0003285699,0.0001814317,0.0001676186,0.0009637738,0.0002410894,0.00006471622,0.0004366743],"genre_scores_gemma":[0.9939981,0.002114849,0.0008614062,0.0004910246,0.0003084313,0.0009330594,0.0003694288,0.00001158553,0.000912219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003064812,"threshold_uncertainty_score":0.01025283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01844251744701554,"score_gpt":0.2868652187913212,"score_spread":0.2684227013443057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}