{"id":"W2111659699","doi":"10.1128/jvi.75.17.8203-8215.2001","title":"Inhibition of Human Immunodeficiency Virus Type 1 Rev Function by a Dominant-Negative Mutant of Sam68 through Sequestration of Unspliced RNA at Perinuclear Bundles","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"","keywords":"Biology; Cytoplasm; RNA; RNA splicing; Nuclear export signal; Nuclear localization sequence; Cell biology; Mutant; Messenger RNA; RNA-binding protein; Nuclear transport; Stimulation; Nucleus; Protein biosynthesis; Molecular biology; Cell nucleus; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001457198,0.0004574613,0.0001934958,0.0001322678,0.0001194884,0.0002147343,0.0003019302,0.000243515,0.0009677873],"category_scores_gemma":[0.00008492629,0.0001714116,0.0002464541,0.00007120276,0.0001978087,0.0001367767,0.0001828172,0.0003577505,0.0004275291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002333171,"about_ca_system_score_gemma":0.0001394708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003444531,"about_ca_topic_score_gemma":0.0006259126,"domain_scores_codex":[0.9999121,0.0000164318,0.00001018422,0.00001573877,0.00002067891,0.00002489424],"domain_scores_gemma":[0.9999005,0.00001482291,0.0000330014,0.00001288791,0.000008416428,0.00003033437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008115103,0.000009560046,0.0000539146,0.00001799169,0.000003233744,0.00003740943,0.000003346234,0.0000239625,0.9992704,0.00005733742,0.0000151908,0.000426592],"study_design_scores_gemma":[0.00002285597,0.0002395974,0.001403148,0.000003962186,0.000007643347,0.0003201481,0.00001196157,0.0008989944,0.9959688,0.00003401081,0.001085264,0.000003501435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966793,0.001206382,0.001165846,0.00004818164,0.0000218084,0.00001031403,0.0000784855,0.00006593668,0.0007236922],"genre_scores_gemma":[0.9962016,0.0004809294,0.001892869,0.00002624239,0.000005203638,0.0000158567,0.0001370957,0.00001617432,0.001224005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009677873,"threshold_uncertainty_score":0.003237605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01729334243847373,"score_gpt":0.2904270019405553,"score_spread":0.2731336595020816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}