{"id":"W2111659699","doi":"10.1128/jvi.75.17.8203-8215.2001","title":"Inhibition of Human Immunodeficiency Virus Type 1 Rev Function by a Dominant-Negative Mutant of Sam68 through Sequestration of Unspliced RNA at Perinuclear Bundles","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"","keywords":"Biology; Cytoplasm; RNA; RNA splicing; Nuclear export signal; Nuclear localization sequence; Cell biology; Mutant; Messenger RNA; RNA-binding protein; Nuclear transport; Stimulation; Nucleus; Protein biosynthesis; Molecular biology; Cell nucleus; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003239456,0.00009246881,0.0002671008,0.00006994704,0.00005655637,0.000003519843,0.00009970004,0.0001445582,0.00005323785],"category_scores_gemma":[0.0001095928,0.00007805521,0.000103208,0.0001124092,0.0001947066,0.00001734969,0.00004739431,0.00012462,0.000001142227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003167424,"about_ca_system_score_gemma":0.00006534834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001419259,"about_ca_topic_score_gemma":0.00003896346,"domain_scores_codex":[0.9988858,0.0001284172,0.0005424499,0.0001198076,0.0001743667,0.0001491971],"domain_scores_gemma":[0.9987791,0.00002020417,0.0006902844,0.0001452195,0.0003334019,0.00003183581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002080405,0.0001601414,0.0004477958,0.00002809397,0.00006385942,0.000005347399,0.0001546028,0.00007081147,0.9964552,0.0001240086,0.0001295229,0.000280201],"study_design_scores_gemma":[0.0009057078,0.006294877,0.002537931,0.00003959961,0.00003456111,0.00007842496,0.0001908005,0.0000435154,0.989215,0.000313066,0.000284111,0.00006237344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979904,0.0007078521,0.0007292844,0.00005795281,0.00005191879,0.00008583466,0.00001193166,0.00000114913,0.0003636452],"genre_scores_gemma":[0.9982287,0.001391435,0.0001602124,0.00003533013,0.00005371438,9.991356e-7,0.000015438,0.0000100321,0.0001041226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007240178,"threshold_uncertainty_score":0.3182999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01729334243847373,"score_gpt":0.2904270019405553,"score_spread":0.2731336595020816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}