{"id":"W2111672031","doi":"10.1093/nar/gkn520","title":"The orphan receptor ERRα interferes with steroid signaling","year":2008,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Association pour la Recherche sur les Tumeurs de la Prostate; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; CNIB","keywords":"Biology; Estrogen-related receptor gamma; Orphan receptor; Nuclear receptor; Estrogen-related receptor alpha; Androgen receptor; Estrogen receptor; Cancer research; Hormone response element; Receptor; Neuron-derived orphan receptor 1; Signal transduction; Inverse agonist; Cell biology; Estrogen receptor beta; GPER; Steroid hormone receptor; Subfamily; Agonist; Prostate cancer; Transcription factor; Genetics; Gene; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002909267,0.0005168784,0.0005305996,0.0002756917,0.0002044529,0.000305528,0.0002374557,0.0002807723,0.002268736],"category_scores_gemma":[0.0002412305,0.0001872948,0.0003395555,0.0001793924,0.0002488218,0.0001916331,0.0002517874,0.000750457,0.0005785465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001835958,"about_ca_system_score_gemma":0.0002676805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000273478,"about_ca_topic_score_gemma":0.0004744708,"domain_scores_codex":[0.9995484,0.0001483513,0.00004083433,0.00005496883,0.0001036495,0.0001036932],"domain_scores_gemma":[0.9998608,0.00003627251,0.00003086404,0.00003164388,0.00001931612,0.0000211097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003315266,0.00006457181,0.0001439775,0.00005566454,0.00001315606,0.00009426456,0.0000145838,0.00007352843,0.9958717,0.0002357027,0.00009333211,0.003007832],"study_design_scores_gemma":[0.00003504717,0.0006950318,0.0008437612,0.000007408777,0.00002447478,0.00035954,0.00002035242,0.0003013831,0.9921575,0.00005377469,0.005498474,0.000003289701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764005,0.006903658,0.007248671,0.0005579149,0.0003110371,0.00008147773,0.0004328156,0.0001833497,0.007880653],"genre_scores_gemma":[0.9775549,0.0061478,0.004413862,0.0002029831,0.00007112275,0.00007377662,0.0006866114,0.00003785819,0.01081112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002268736,"threshold_uncertainty_score":0.007589638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02816360916447578,"score_gpt":0.3011201342197383,"score_spread":0.2729565250552625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}