{"id":"W2111715251","doi":"10.1099/vir.0.030296-0","title":"Herpes simplex virus type 2 virion host shutoff protein suppresses innate dsRNA antiviral pathways in human vaginal epithelial cells","year":2011,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Innate immune system; IRF3; TLR3; TLR2; Sendai virus; Interferon; Virology; Herpes simplex virus; RIG-I; Transfection; Interferon type I; Virus; MDA5; HEK 293 cells; Immune system; Cell culture; Toll-like receptor; RNA interference; Immunology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211932,0.0002355472,0.000549674,0.0003875285,0.0001006555,0.00001633811,0.0001394236,0.0002200468,0.0005289049],"category_scores_gemma":[0.00003391053,0.0001819577,0.0001512932,0.0002161032,0.0001468822,0.0001917938,0.00005437824,0.0004269654,0.00005574314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001000499,"about_ca_system_score_gemma":0.0001436362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006986776,"about_ca_topic_score_gemma":0.000193021,"domain_scores_codex":[0.9983145,0.0002134228,0.000649411,0.0002183672,0.0002087504,0.0003955435],"domain_scores_gemma":[0.9991267,0.00002031073,0.0003435573,0.0002032451,0.0001645738,0.0001416608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001232447,0.001294476,0.005453181,0.00002252455,0.0001883633,0.001393536,0.0003615155,0.00000893455,0.9717312,0.0002855504,0.0002603681,0.01776784],"study_design_scores_gemma":[0.005009261,0.00476434,0.1324803,0.00006526335,0.0001671393,0.0004010325,0.00002540783,0.0000576858,0.8158912,0.001185515,0.03971238,0.0002404788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972996,0.0001491952,0.00005014113,0.0001245099,0.0004712706,0.000260616,0.00002117641,0.00001860906,0.001604933],"genre_scores_gemma":[0.997803,0.0001208232,0.0009453231,0.0002651374,0.0004898659,0.000007993206,0.000007492986,0.00003317434,0.0003271464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.15584,"threshold_uncertainty_score":0.7420021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0349879384526197,"score_gpt":0.2859567739596234,"score_spread":0.2509688355070037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}