{"id":"W2111715251","doi":"10.1099/vir.0.030296-0","title":"Herpes simplex virus type 2 virion host shutoff protein suppresses innate dsRNA antiviral pathways in human vaginal epithelial cells","year":2011,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Innate immune system; IRF3; TLR3; TLR2; Sendai virus; Interferon; Virology; Herpes simplex virus; RIG-I; Transfection; Interferon type I; Virus; MDA5; HEK 293 cells; Immune system; Cell culture; Toll-like receptor; RNA interference; Immunology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001616637,0.0001902266,0.0002608218,0.0001205459,0.0001208043,0.000428481,0.0001066548,0.000195864,0.001173789],"category_scores_gemma":[0.0001413847,0.000116243,0.0002529006,0.0001567209,0.0001247659,0.0001383402,0.0001822858,0.000343999,0.0003641574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001450415,"about_ca_system_score_gemma":0.0002357817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005578516,"about_ca_topic_score_gemma":0.0005519494,"domain_scores_codex":[0.9998154,0.00003765877,0.00002159476,0.00002746795,0.00004612148,0.00005178511],"domain_scores_gemma":[0.9999166,0.00002218702,0.00001439578,0.0000193355,0.00001200309,0.00001544645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001209577,0.00003247894,0.0003523598,0.00003525089,0.000004708409,0.00006958732,0.00002669226,0.00002607706,0.9981787,0.00004558773,0.00004141845,0.001066053],"study_design_scores_gemma":[0.0000215202,0.000527932,0.008793309,0.000007347943,0.00001401019,0.0005574204,0.0001482396,0.0007810861,0.9859534,0.00003922038,0.003152373,0.000004141298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960568,0.001750824,0.0007956717,0.0000543563,0.00002450395,0.00001973883,0.0003287345,0.00004298973,0.0009263776],"genre_scores_gemma":[0.9964922,0.0007081889,0.0005745977,0.00003487989,0.000007405105,0.00002297028,0.0005925562,0.000009244985,0.001558067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001173789,"threshold_uncertainty_score":0.003926754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0349879384526197,"score_gpt":0.2859567739596234,"score_spread":0.2509688355070037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}