{"id":"W2111735661","doi":"10.1093/hmg/ddq558","title":"SOX9 controls epithelial branching by activating RET effector genes during kidney development","year":2011,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Oulun Yliopisto; Medizinischen Hochschule Hannover; McGill University; European Commission; Association pour la Recherche sur le Cancer; Harvard University","keywords":"Kidney development; Biology; SOX9; Nephron; Kidney; Glial cell line-derived neurotrophic factor; Ureteric bud; Mesenchyme; Internal medicine; Zebrafish; Cell biology; Endocrinology; Genetics; Gene; Gene expression; Embryonic stem cell; Embryo; Medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006907801,0.0001800733,0.0001034937,0.0001847865,0.0001352997,0.0002549218,0.000147652,0.0001410206,0.0008503773],"category_scores_gemma":[0.00009537998,0.000104349,0.0000903555,0.00008459619,0.0001889907,0.0001148936,0.0001880137,0.0001376452,0.0003326823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551913,"about_ca_system_score_gemma":0.0001604941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008283483,"about_ca_topic_score_gemma":0.001533658,"domain_scores_codex":[0.9999068,0.00001551538,0.000007031381,0.00002320096,0.00002684796,0.00002068312],"domain_scores_gemma":[0.999917,0.00001146432,0.0000282047,0.000007624226,0.000009958869,0.00002556836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000511803,0.000003327279,0.0007449244,0.000008763111,0.00000122436,0.0001557202,0.00001274174,0.00004132212,0.9980925,0.0001154854,0.00001212325,0.0007607085],"study_design_scores_gemma":[0.00001034954,0.00005744435,0.03278933,0.000005643402,0.000009533432,0.001037903,0.00005874008,0.00105593,0.9608623,0.0001628762,0.003946006,0.000003990205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950913,0.0008468957,0.002010106,0.00003963813,0.00001249321,0.000005873,0.0002094644,0.00007245631,0.001711693],"genre_scores_gemma":[0.9964364,0.0003732645,0.0006831309,0.000008369004,0.000002917212,0.000003771475,0.0001266808,0.00001332629,0.002352135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008503773,"threshold_uncertainty_score":0.00284481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008530871824261122,"score_gpt":0.2194540737876943,"score_spread":0.2109232019634332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}