{"id":"W2111759346","doi":"10.1039/c2cc37110c","title":"Racemic marinopyrrole B by total synthesis","year":2012,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Pyrrole; Ring (chemistry); Chemistry; Alkylation; Allylic rearrangement; Stereochemistry; Tsuji–Trost reaction; Total synthesis; Acceptor; Michael reaction; Medicinal chemistry; Combinatorial chemistry; Catalysis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002253673,0.0006213235,0.0004274511,0.0005602562,0.0004035602,0.00040573,0.0005062594,0.0003256202,0.003354805],"category_scores_gemma":[0.0001887913,0.0002591956,0.0003094678,0.0004245008,0.0002279714,0.0003814125,0.0004239577,0.0007288147,0.0025275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003317056,"about_ca_system_score_gemma":0.0006790457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008033855,"about_ca_topic_score_gemma":0.001079048,"domain_scores_codex":[0.9998056,0.00002426642,0.00001727353,0.0000498548,0.00004691565,0.00005604219],"domain_scores_gemma":[0.9999205,0.000007130569,0.00001165133,0.00001898369,0.0000202492,0.00002141309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001720954,0.00008421357,0.0001006655,0.0003004304,0.00002305098,0.0003695146,0.0001100079,0.0009066449,0.9666698,0.005331049,0.001181553,0.02475099],"study_design_scores_gemma":[0.00006054749,0.0007184336,0.0005309369,0.00003309446,0.00004100053,0.0007321477,0.00002940696,0.001128686,0.9089968,0.0009358464,0.08674452,0.00004861649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6441653,0.01667304,0.2152454,0.000932625,0.001185766,0.002152633,0.008935922,0.003565566,0.1071437],"genre_scores_gemma":[0.8891185,0.01109698,0.07284946,0.0002682144,0.00007062285,0.0004844247,0.003223433,0.000240021,0.02264844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003354805,"threshold_uncertainty_score":0.01122296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02305501249747199,"score_gpt":0.2741432813403583,"score_spread":0.2510882688428863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}