{"id":"W2111780494","doi":"10.1002/jmv.21773","title":"Neurovirulence and latency of drug‐resistant clinical herpes simplex viruses in animal models","year":2010,"lang":"en","type":"article","venue":"Journal of Medical Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Virology; Herpes simplex virus; Mutant; Viral replication; DNA polymerase; Thymidine kinase; Virus; DNA replication; Molecular biology; Foscarnet; DNA; Gene; Herpesviridae; Viral disease; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004831298,0.000782199,0.0003863274,0.001183958,0.0002890228,0.0005620152,0.0003463943,0.0004423749,0.001347847],"category_scores_gemma":[0.0003294513,0.0002676377,0.0002900557,0.0003220949,0.0004442844,0.0007074947,0.0002595096,0.001168569,0.0004229883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005978044,"about_ca_system_score_gemma":0.0002985399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001330709,"about_ca_topic_score_gemma":0.001814689,"domain_scores_codex":[0.999537,0.0001089902,0.00004366053,0.00009350835,0.0001068235,0.0001100205],"domain_scores_gemma":[0.9996437,0.00004925927,0.0001073918,0.00004593125,0.0000495324,0.0001042268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002352214,0.001217062,0.003990748,0.0001375875,0.00005161843,0.0002585583,0.000167848,0.0002214844,0.9861183,0.0003308459,0.0002465783,0.004907185],"study_design_scores_gemma":[0.0002783003,0.03190412,0.06248968,0.0001229726,0.000242079,0.003969278,0.0006886863,0.003990266,0.8884392,0.0006881893,0.007107445,0.0000796015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929717,0.002780851,0.001393271,0.00006733547,0.00004700191,0.0001147038,0.0006013657,0.00005480949,0.001969038],"genre_scores_gemma":[0.9910919,0.00244935,0.001633578,0.00004685686,0.00001713177,0.0002284204,0.0009122801,0.00001898008,0.003601518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001347847,"threshold_uncertainty_score":0.004508972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04493105473819628,"score_gpt":0.385474403188031,"score_spread":0.3405433484498347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}