{"id":"W2111799732","doi":"10.1016/j.jhep.2007.08.019","title":"Susceptibility to type 1 autoimmune hepatitis is associated with shared amino acid sequences at positions 70–74 of the HLA-DRB1 molecule","year":2007,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Autoimmune hepatitis; Epitope; Human leukocyte antigen; HLA-DRB1; Allele; Hypervariable region; Amino acid; Peptide sequence; Genetics; Gene; Biology; Hepatitis; Medicine; Immunology; Antigen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004023844,0.0001213071,0.000466654,0.0001047383,0.0001292235,0.000007186449,0.0002138266,0.0001044679,0.0006126385],"category_scores_gemma":[0.0003175774,0.0000758013,0.0001793348,0.0003291067,0.0001938038,0.0000802319,0.00009245009,0.0002645485,0.00001046676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003023987,"about_ca_system_score_gemma":0.0003546386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007080983,"about_ca_topic_score_gemma":0.001075695,"domain_scores_codex":[0.9986538,0.0001499552,0.0005137672,0.0001180811,0.0003114623,0.0002528824],"domain_scores_gemma":[0.9982998,0.0001092012,0.0004514429,0.0003160256,0.0006766872,0.0001468231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007316414,0.0003229048,0.9379524,0.00002256962,0.0003036171,0.0001320217,0.0005129402,0.000002549606,0.05731409,0.0000223252,0.002563797,0.0001191701],"study_design_scores_gemma":[0.0009000293,0.001763619,0.962823,0.0001657105,0.0003138892,0.0005514568,0.0001267624,0.00002867969,0.03295536,0.00005520349,0.0002351667,0.00008117236],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958445,0.000547739,0.00005743346,0.002660147,0.0002150551,0.0001839969,0.00005414683,0.000009517355,0.0004275094],"genre_scores_gemma":[0.9981278,0.0000602145,0.0002541864,0.001221435,0.00002988286,9.964331e-7,0.00001393001,0.00001105348,0.0002804692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02487058,"threshold_uncertainty_score":0.6707962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01803411982471548,"score_gpt":0.2788182076041054,"score_spread":0.2607840877793899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}