{"id":"W2111799732","doi":"10.1016/j.jhep.2007.08.019","title":"Susceptibility to type 1 autoimmune hepatitis is associated with shared amino acid sequences at positions 70–74 of the HLA-DRB1 molecule","year":2007,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Autoimmune hepatitis; Epitope; Human leukocyte antigen; HLA-DRB1; Allele; Hypervariable region; Amino acid; Peptide sequence; Genetics; Gene; Biology; Hepatitis; Medicine; Immunology; Antigen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004860561,0.0007068958,0.0004606156,0.001277462,0.0005521909,0.0004100233,0.0002634136,0.0007948599,0.003746362],"category_scores_gemma":[0.001315371,0.0002923077,0.0003065425,0.0007521771,0.0004584363,0.0002844905,0.0003902417,0.0006963657,0.0004271704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001477739,"about_ca_system_score_gemma":0.0001774792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005461286,"about_ca_topic_score_gemma":0.0005016025,"domain_scores_codex":[0.9993463,0.0003356738,0.0000453047,0.00008818315,0.00006660217,0.0001179635],"domain_scores_gemma":[0.9980752,0.0006002149,0.0008156145,0.0001128704,0.00008281161,0.0003132077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00459238,0.0007283743,0.8591279,0.0001309127,0.0005269576,0.004693054,0.0005175361,0.0004981405,0.1162129,0.0006848737,0.0006604771,0.01162661],"study_design_scores_gemma":[0.0001231073,0.000947806,0.9827407,0.00002526174,0.0002067709,0.01109025,0.0002709258,0.0007180964,0.002585909,0.0005594717,0.0007043811,0.00002722608],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990852,0.0001296972,0.0001155766,0.0000497834,0.000007206602,0.000002622734,0.00002390146,0.000008359749,0.0005776259],"genre_scores_gemma":[0.9995047,0.00006095862,0.0001161172,0.00002424644,0.00002818896,0.00000191229,0.00004206063,0.00000486481,0.0002168457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003746362,"threshold_uncertainty_score":0.01253283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01803411982471548,"score_gpt":0.2788182076041054,"score_spread":0.2607840877793899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}