{"id":"W2111804964","doi":"10.1093/nar/gkr885","title":"Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs","year":2011,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Biology; Oligonucleotide; Peptide nucleic acid; Nucleic acid; Peptide; Biochemistry; microRNA; RNA; Molecular biology; Cell biology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002608643,0.0001824477,0.0001908929,0.0000964362,0.0001374558,0.000293616,0.0002233782,0.0003874911,0.0005513594],"category_scores_gemma":[0.0005838324,0.0002112483,0.0001449744,0.00008372216,0.0002827669,0.0003043323,0.000141968,0.0003785314,0.0002673191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000469598,"about_ca_system_score_gemma":0.000253614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005761239,"about_ca_topic_score_gemma":0.0008467322,"domain_scores_codex":[0.9997655,0.00006618615,0.00001876891,0.00003968373,0.00007829449,0.0000316469],"domain_scores_gemma":[0.9997237,0.0001335532,0.00006907259,0.00001483184,0.00002804686,0.00003072013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000386395,0.000005526357,0.00004163654,0.00001530522,0.000001047733,0.00002386318,0.000005563702,0.0001489067,0.9994568,0.00009790819,0.000004500461,0.0001602852],"study_design_scores_gemma":[0.000009826704,0.0001074658,0.0005801985,0.000001648116,0.000003330232,0.00009521231,0.00000986302,0.001066524,0.9976225,0.00003672673,0.0004635419,0.000003078357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960891,0.0006727173,0.002160405,0.00005087349,0.000005957328,0.00001454483,0.00007359409,0.000014881,0.0009178331],"genre_scores_gemma":[0.9966236,0.0003866054,0.002408131,0.00002843702,0.000004656697,0.00002012898,0.0001859613,0.000008648254,0.0003337378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005761239,"threshold_uncertainty_score":0.00340718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02747590179045935,"score_gpt":0.2928625642664824,"score_spread":0.2653866624760231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}