{"id":"W2111893619","doi":"10.1126/science.1083022","title":"Essential Role of Fkbp6 in Male Fertility and Homologous Chromosome Pairing in Meiosis","year":2003,"lang":"en","type":"article","venue":"Science","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":217,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Synapsis; Homologous chromosome; Synaptonemal complex; Meiosis; Biology; Genetics; Homologous recombination; Genetic recombination; Chromosomal crossover; Chromosome; Bivalent (engine); Recombination; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005281334,0.00005515963,0.0000787666,0.00006071827,0.00002528849,0.000008183912,0.0001412683,0.00004582278,0.00001295133],"category_scores_gemma":[0.0001666138,0.00005544017,0.00001535582,0.0002289475,0.0002346402,0.000006861584,0.00009355054,0.00003432253,8.337897e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001406167,"about_ca_system_score_gemma":0.00008246639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003501219,"about_ca_topic_score_gemma":0.0001420784,"domain_scores_codex":[0.9992729,0.00003668335,0.0001166032,0.0002843536,0.000102697,0.0001867667],"domain_scores_gemma":[0.999717,0.000004671078,0.00002819005,0.0001907778,0.00002220311,0.00003714226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007358159,0.00003426859,0.03900747,0.000005704036,6.807008e-7,0.000002528152,0.00005456221,0.00001409955,0.9602708,0.00008820397,5.814284e-7,0.0005137861],"study_design_scores_gemma":[0.0001554614,0.00005777539,0.06483068,0.00000750164,9.291186e-7,0.000009185782,0.00008242239,0.0001203698,0.9340889,0.0005321435,0.00005748121,0.00005710462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985226,0.0003884497,0.00004324108,0.000008606489,0.00004440157,0.00007212508,0.000001429353,0.000002797131,0.0009163773],"genre_scores_gemma":[0.9991139,0.00001426458,0.0007981219,0.00001501312,0.000003645923,0.000005802784,5.893861e-7,0.000002955097,0.00004566712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02618181,"threshold_uncertainty_score":0.2260785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004836069378852047,"score_gpt":0.2276463532014575,"score_spread":0.2228102838226055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}