{"id":"W2111957505","doi":"10.1091/mbc.e05-03-0186","title":"Transendothelial Migration of Melanoma Cells Involves N-Cadherin-mediated Adhesion and Activation of the β-Catenin Signaling Pathway","year":2005,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Cadherin; Catenin; Cell biology; Beta-catenin; Melanoma; Cell adhesion; Extravasation; Cancer cell; Cell migration; Cancer research; Signal transduction; Cell; Immunology; Cancer; Wnt signaling pathway; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087159,0.0004141211,0.0001814781,0.0002591148,0.0002040359,0.0003932384,0.0001135786,0.0002311522,0.0006682841],"category_scores_gemma":[0.00008604208,0.0001627865,0.0001730354,0.0001735557,0.0001989476,0.0002622503,0.0001907031,0.0004361433,0.0002899158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003547489,"about_ca_system_score_gemma":0.0002592991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001006004,"about_ca_topic_score_gemma":0.00144605,"domain_scores_codex":[0.9998441,0.00002267679,0.0000120196,0.00004153193,0.00005106128,0.00002865636],"domain_scores_gemma":[0.9999419,0.000005399234,0.00001866922,0.000005193092,0.00001157353,0.00001716277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001501085,0.000008363271,0.0001485442,0.00001891122,0.000001968838,0.00003581043,0.000007079388,0.000009990737,0.9990574,0.00006211788,0.00001460214,0.0006202767],"study_design_scores_gemma":[0.00001371941,0.0001476566,0.01766847,0.00001077175,0.00001477779,0.0004779276,0.00004801274,0.001069703,0.9761553,0.00007710329,0.004311114,0.000005349666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857923,0.00505947,0.005426419,0.0001360042,0.00003275322,0.00004001799,0.0001827685,0.0000937025,0.003236482],"genre_scores_gemma":[0.9932135,0.001955473,0.001845355,0.00003531294,0.000006463292,0.00002089212,0.0002223105,0.000005280682,0.002695343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001006004,"threshold_uncertainty_score":0.002573907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006694796398962879,"score_gpt":0.204275972346381,"score_spread":0.1975811759474181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}