{"id":"W2112068705","doi":"10.3109/10428194.2015.1068306","title":"Silibinin suppresses NPM-ALK, potently induces apoptosis and enhances chemosensitivity in ALK-positive anaplastic large cell lymphoma","year":2015,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Silymarin and Mushroom Poisoning","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Silibinin; Anaplastic lymphoma kinase; Cancer research; Anaplastic large-cell lymphoma; Survivin; Protein kinase B; Chemistry; Cell growth; Apoptosis; Biology; Lymphoma; Medicine; Immunology; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000705537,0.0002271256,0.0001652113,0.0001862627,0.0001053901,0.0001383887,0.0000904498,0.0001281354,0.000751373],"category_scores_gemma":[0.00007682455,0.00006278296,0.0001401709,0.0001056381,0.0001308877,0.0001594793,0.00009654036,0.0002816262,0.0001657095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001417978,"about_ca_system_score_gemma":0.0001191236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003298083,"about_ca_topic_score_gemma":0.001063536,"domain_scores_codex":[0.9999683,0.000007666257,0.00000375254,0.000004316124,0.000008176658,0.000007759524],"domain_scores_gemma":[0.9999747,0.000004032619,0.000008012703,0.000002845982,0.000002945933,0.000007411839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003033562,0.00008739824,0.0002262243,0.00003146781,0.000004858999,0.00006449636,0.00001180065,0.00005892128,0.9958461,0.00003928463,0.00004386013,0.003282297],"study_design_scores_gemma":[0.00004447749,0.001022387,0.004277279,0.00000333731,0.00001579702,0.0003221186,0.00002236328,0.0007746979,0.9920283,0.00002969258,0.00145724,0.000002346801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947011,0.002405233,0.0009908305,0.00006784766,0.00001936,0.0000228791,0.00009438094,0.00005819806,0.001640111],"genre_scores_gemma":[0.9972525,0.0008809572,0.0006132798,0.0000290804,0.00001054723,0.00001559865,0.0001462128,0.000005651435,0.001046094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000751373,"threshold_uncertainty_score":0.002513587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267269262193477,"score_gpt":0.2413551820654554,"score_spread":0.2286824894435207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}