{"id":"W2112084205","doi":"10.1002/gene.20019","title":"Transition nuclear proteins are required for normal chromatin condensation and functional sperm development","year":2004,"lang":"en","type":"article","venue":"genesis","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute","keywords":"Protamine; Chromatin; Biology; Histone; Sperm; Cell biology; Prophase; Intracytoplasmic sperm injection; Sterility; Chromatin remodeling; Andrology; Genetics; Embryo; DNA; Gene; Biochemistry; Meiosis; In vitro fertilisation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103313,0.0003112211,0.0001794202,0.0002377246,0.0001664641,0.0002997826,0.0001778655,0.0002747528,0.001952421],"category_scores_gemma":[0.0002539917,0.0001358001,0.0001299441,0.0001120794,0.0002838974,0.0001915735,0.0002289603,0.0002612396,0.0007329729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001992707,"about_ca_system_score_gemma":0.0002779647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005156216,"about_ca_topic_score_gemma":0.0006922524,"domain_scores_codex":[0.9998987,0.00001347901,0.00001035126,0.00002211187,0.00003365852,0.00002170378],"domain_scores_gemma":[0.9997484,0.00003384891,0.00009311491,0.00001969567,0.00002730356,0.0000776689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001014916,0.000006410972,0.0005831541,0.00003278736,0.000003780706,0.0002088112,0.0000167794,0.00004229187,0.9962095,0.0002536436,0.00005117201,0.002490051],"study_design_scores_gemma":[0.00003507184,0.0003140117,0.03357257,0.00001229868,0.00002615805,0.002724202,0.00004607908,0.0004946014,0.9518617,0.0002326145,0.01067182,0.000008789057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800584,0.004958977,0.01078172,0.0001421814,0.00005652496,0.00002527205,0.0007237286,0.000533839,0.002719391],"genre_scores_gemma":[0.9912225,0.001144611,0.003383904,0.00002620503,0.00001580714,0.00001718711,0.000957911,0.0000441189,0.00318784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001952421,"threshold_uncertainty_score":0.006531477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02515463739779812,"score_gpt":0.2237974886672078,"score_spread":0.1986428512694097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}