{"id":"W2112110584","doi":"10.1186/1742-4690-11-38","title":"Switching and emergence of CTL epitopes in HIV-1 infection","year":2014,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology; Michael Smith Health Research BC","keywords":"CTL*; Epitope; Human leukocyte antigen; Virology; Cytotoxic T cell; Biology; Antigen; Mutation; Gene; Group-specific antigen; Genetics; Immunology; Human immunodeficiency virus (HIV); CD8; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002242322,0.0001386775,0.0001286196,0.0002322225,0.000204273,0.0002237867,0.0001058642,0.00031471,0.0009185077],"category_scores_gemma":[0.0004960674,0.0000655156,0.00008649601,0.0001252405,0.0002228785,0.0001548581,0.0002647281,0.0002611709,0.0001607013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001984777,"about_ca_system_score_gemma":0.00009627586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003048446,"about_ca_topic_score_gemma":0.0002156681,"domain_scores_codex":[0.99988,0.00002767535,0.000009051628,0.00002020916,0.00002246703,0.00004069763],"domain_scores_gemma":[0.9998554,0.00005494483,0.0000318634,0.00001194747,0.00001341851,0.00003244686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001948685,0.0004985859,0.4280213,0.0002051124,0.00004132947,0.004070407,0.001053115,0.000899929,0.4846369,0.0005821688,0.0004697564,0.07757264],"study_design_scores_gemma":[0.0001466918,0.002231758,0.8276535,0.00009099803,0.00009231202,0.03513499,0.0008915104,0.002923115,0.1254246,0.00135537,0.004023775,0.00003132765],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991052,0.0003367309,0.0001461209,0.00001108324,0.000001990567,0.000005973286,0.00001065384,0.000004229635,0.0003780522],"genre_scores_gemma":[0.9995931,0.0001037862,0.0001026349,0.0000188514,0.000004356372,0.000005205856,0.00003332168,7.487925e-7,0.0001379958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009185077,"threshold_uncertainty_score":0.003072739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007795912497248542,"score_gpt":0.2435656139858705,"score_spread":0.235769701488622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}