{"id":"W2112110584","doi":"10.1186/1742-4690-11-38","title":"Switching and emergence of CTL epitopes in HIV-1 infection","year":2014,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology; Michael Smith Health Research BC","keywords":"CTL*; Epitope; Human leukocyte antigen; Virology; Cytotoxic T cell; Biology; Antigen; Mutation; Gene; Group-specific antigen; Genetics; Immunology; Human immunodeficiency virus (HIV); CD8; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002214062,0.00006796051,0.0001762158,0.0001236766,0.00004039192,0.000001615636,0.00004826683,0.0001262057,0.0002257714],"category_scores_gemma":[0.0001312927,0.00005736872,0.00002269411,0.00006958932,0.00009996873,0.0000349282,0.00004726518,0.0001598929,0.0002305132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000086725,"about_ca_system_score_gemma":0.00001230893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005132823,"about_ca_topic_score_gemma":0.0002687877,"domain_scores_codex":[0.9992417,0.0002252721,0.0001503184,0.0001577023,0.00001496006,0.0002101157],"domain_scores_gemma":[0.9996952,0.0001160345,0.00004512884,0.0001154975,0.00001368671,0.00001447346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007838088,0.00006739583,0.724685,0.00001531505,0.0000339126,0.000002467252,0.000158552,0.000006641915,0.2505575,0.001286506,0.0002570053,0.02285136],"study_design_scores_gemma":[0.001486549,0.0008683764,0.963898,0.00001217147,0.00001264262,0.00004022386,0.00002742671,0.00003350175,0.02243845,0.0005925681,0.01050312,0.00008697108],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973018,0.0007275206,0.0005381474,0.0002212536,0.000120013,0.00007589253,0.000005098426,0.00001299707,0.0009972535],"genre_scores_gemma":[0.9994145,0.0002884186,0.00005230671,0.00003127356,0.00001137845,0.000009670587,0.00002088899,0.000004206293,0.0001673264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2392131,"threshold_uncertainty_score":0.2962857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007795912497248542,"score_gpt":0.2435656139858705,"score_spread":0.235769701488622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}