{"id":"W2112198303","doi":"10.1152/ajpgi.00142.2014","title":"Redeeming an old foe: protective as well as pathophysiological roles for tumor necrosis factor in inflammatory bowel disease","year":2014,"lang":"en","type":"review","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Government of Canada; National Institute of Diabetes and Digestive and Kidney Diseases; Crohn's and Colitis Foundation of America","keywords":"Tumor necrosis factor alpha; Inflammatory bowel disease; Ulcerative colitis; Medicine; Inflammation; Disease; Immunology; Gastrointestinal tract; Pathophysiology; Crohn's disease; Receptor; Tumor necrosis factor α; Colitis; Bioinformatics; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004176565,0.000572417,0.001012131,0.001727567,0.0002911718,0.0008914936,0.000696522,0.001140145,0.003471853],"category_scores_gemma":[0.0007251626,0.0001739389,0.0003579502,0.001470663,0.0004652375,0.001114356,0.0006705198,0.001572537,0.002311658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004648303,"about_ca_system_score_gemma":0.000742837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00071901,"about_ca_topic_score_gemma":0.001404546,"domain_scores_codex":[0.9998516,0.00003073279,0.00002266626,0.0000260997,0.00005576864,0.00001311333],"domain_scores_gemma":[0.9997782,0.00009871978,0.00003044188,0.000006724324,0.00005874455,0.00002718703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008041687,0.00004263184,0.0002026082,0.01215276,0.0000643211,0.0002559865,0.00007842967,0.000145107,0.001040854,0.003203201,0.03261689,0.9501168],"study_design_scores_gemma":[0.00001485482,0.00007025982,0.0009638153,0.003939152,0.00007451468,0.002165865,0.00008281718,0.00003948807,0.0002841043,0.001908147,0.9904418,0.0000152537],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001118893,0.9983127,0.00008831562,0.0003809743,0.0002518201,0.000002972131,0.00001391446,0.000005386496,0.0008319347],"genre_scores_gemma":[0.0006071321,0.9983025,0.0001337928,0.0002175889,0.0001492873,0.000004188204,0.00001911264,0.000001349549,0.0005649972],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003471853,"threshold_uncertainty_score":0.0116145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009765649696006557,"score_gpt":0.2648389734902319,"score_spread":0.2550733237942253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}