{"id":"W2112292025","doi":"10.1128/jvi.01707-10","title":"Epitope Mapping of HIV-Specific CD8 <sup>+</sup> T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function","year":2010,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Epitope; Biology; CD8; T cell; Immunology; Virology; Flow cytometry; Tumor necrosis factor alpha; Epitope mapping; Cytotoxic T cell; Immune system; Antigen; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001649838,0.0002331554,0.000147256,0.000124395,0.00007535255,0.0002433558,0.00008428585,0.000190953,0.0009496644],"category_scores_gemma":[0.0001950836,0.00009531106,0.0000912181,0.00007527383,0.0001703329,0.0001969473,0.0001247098,0.0002765516,0.0002325859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007745504,"about_ca_system_score_gemma":0.00003919093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009557965,"about_ca_topic_score_gemma":0.000113578,"domain_scores_codex":[0.9999369,0.00001424836,0.000006157727,0.00001861263,0.000009679392,0.00001432444],"domain_scores_gemma":[0.9998789,0.00004044277,0.00003336747,0.00001866519,0.00001172449,0.00001696997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001894728,0.00001833568,0.00761176,0.0000275239,0.000003898049,0.00003454243,0.00003788458,0.00009724533,0.9864984,0.00002535582,0.00001260343,0.005443084],"study_design_scores_gemma":[0.00002640741,0.002193957,0.1767161,0.00001935659,0.00004645242,0.001887387,0.0002274106,0.00318282,0.8142065,0.0003934741,0.001089151,0.00001087585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982691,0.0003092438,0.001155776,0.00001339518,0.000001633274,0.000007031349,0.00003786325,0.00001148488,0.000194401],"genre_scores_gemma":[0.9984971,0.0001582182,0.001058167,0.00002352879,0.000003845965,0.00001121738,0.00007027227,0.000003429099,0.00017423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009496644,"threshold_uncertainty_score":0.003176928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01930879001302996,"score_gpt":0.2354424634355314,"score_spread":0.2161336734225015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}