{"id":"W2112331687","doi":"10.1186/cc8208","title":"Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza","year":2009,"lang":"en","type":"article","venue":"Critical Care","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":378,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre; University Health Network","funders":"National Institutes of Health; Junta de Castilla y León; Canadian Institutes of Health Research; Li Ka Shing Foundation; Institute of Museum and Library Services","keywords":"Medicine; Immune system; Immunology; Chemokine; Antibody; Innate immune system; Cytokine; Viral load; Influenza A virus; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003174559,0.0002234183,0.0003910162,0.0001886358,0.0001305348,0.00005054475,0.00011533,0.000297431,0.00008131113],"category_scores_gemma":[0.006871946,0.0001846618,0.00006885271,0.0002787605,0.0003182104,0.000148866,0.0001015791,0.000975294,0.00007219638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002006562,"about_ca_system_score_gemma":0.0001969217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005900136,"about_ca_topic_score_gemma":0.00002229893,"domain_scores_codex":[0.9981229,0.0001651594,0.0002566961,0.0003964767,0.0004826959,0.0005761175],"domain_scores_gemma":[0.9982699,0.0007060173,0.00001354475,0.0003183602,0.0003895827,0.0003026676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03419293,0.0003975283,0.6851207,0.001505787,0.0001027927,0.006014551,0.02779784,0.000006028014,0.2071204,0.006129972,0.004529235,0.02708226],"study_design_scores_gemma":[0.003103166,0.001780142,0.9777215,0.0004301153,0.0000628327,0.0001727907,0.0039744,0.000006155828,0.001655884,0.0008369234,0.009930773,0.0003253001],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784238,0.01154774,0.000001137808,0.003150068,0.00003908448,0.0003738413,0.00003979043,0.00009034591,0.006334201],"genre_scores_gemma":[0.9909297,0.00009278789,0.0001441819,0.008507088,0.0001213284,0.00001972491,0.000004525557,0.00002041582,0.0001603042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2926008,"threshold_uncertainty_score":0.8226858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06014180852519473,"score_gpt":0.414402654665408,"score_spread":0.3542608461402133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}