{"id":"W2112366801","doi":"10.1083/jcb.200110017","title":"TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal","year":2001,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Tropomyosin receptor kinase A; Low-affinity nerve growth factor receptor; Trk receptor; Biology; Neurotrophin; Nerve growth factor; Gene silencing; Cell biology; Programmed cell death; Receptor; Neuron; Neuroscience; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001590998,0.000282382,0.0002255434,0.0001513192,0.0002522334,0.0003825547,0.000325823,0.0002241794,0.001181661],"category_scores_gemma":[0.0001923094,0.0001516473,0.0002154408,0.00007239739,0.0002867215,0.0002710473,0.0002706941,0.0008695969,0.0005820509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004328014,"about_ca_system_score_gemma":0.0002985052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006879367,"about_ca_topic_score_gemma":0.001833999,"domain_scores_codex":[0.99981,0.00002678981,0.00001988626,0.00003730416,0.00005230958,0.00005365824],"domain_scores_gemma":[0.9998189,0.00003308782,0.00004780399,0.00002779989,0.00001547645,0.00005700316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003857857,0.00001098887,0.00007326793,0.00001630127,0.000002408015,0.00003339789,0.00001131773,0.00004245671,0.9987949,0.0001758617,0.00001773705,0.0007827841],"study_design_scores_gemma":[0.00001228203,0.0002004073,0.001607132,0.000006761064,0.00001165465,0.0001695709,0.00002070143,0.0007609916,0.9960681,0.00006835808,0.001071362,0.000002725661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991876,0.001283659,0.00424847,0.00008942642,0.00002797648,0.00001768813,0.0001636478,0.00008878797,0.002204286],"genre_scores_gemma":[0.9923195,0.00113019,0.002939603,0.00003303502,0.00001107464,0.00002880665,0.0002474238,0.00002305794,0.003267138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001181661,"threshold_uncertainty_score":0.00395304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02701725025856182,"score_gpt":0.2549723452945089,"score_spread":0.2279550950359471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}