{"id":"W2112374340","doi":"10.1128/mcb.21.18.6332-6345.2001","title":"S Phase-Specific Proteolytic Cleavage Is Required To Activate Stable DNA Binding by the CDP/Cut Homeodomain Protein","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Medical Research Council; Medical Research Council Canada","keywords":"Biology; Molecular biology; DNA; DNA-binding protein; Immunoprecipitation; Proteolysis; Cleavage (geology); Gene isoform; Biochemistry; Transcription factor; Cell biology; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003307578,0.0003264208,0.000273572,0.0000654349,0.0002603524,0.00007832621,0.0003924124,0.0002803329,0.00003773066],"category_scores_gemma":[0.00002657388,0.0002655077,0.0001180407,0.000196925,0.0001718561,0.000005344798,0.0002774091,0.0001646342,0.00003311182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003040894,"about_ca_system_score_gemma":0.00004248448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002212821,"about_ca_topic_score_gemma":0.000006568063,"domain_scores_codex":[0.9980848,0.0001709246,0.0003187975,0.0007070463,0.0001172417,0.0006012073],"domain_scores_gemma":[0.9989979,0.000009392507,0.0001224513,0.0006515537,0.00004587609,0.000172864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001456656,0.0001242991,0.00006846993,0.00001330672,0.00007313801,0.00002135478,0.00007461673,0.000003373823,0.9941788,0.0003285313,0.001455814,0.003512577],"study_design_scores_gemma":[0.001122753,0.0007796259,0.000007270352,0.00001205872,0.00001699921,0.00003739335,0.0001038208,0.00008881849,0.8649789,0.0003633525,0.1321606,0.0003283328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762546,0.001341824,0.01964175,0.0007709371,0.00008296347,0.0009839823,0.00008975523,0.00002079792,0.000813415],"genre_scores_gemma":[0.996437,0.0001881299,0.0005766707,0.0006709918,0.00009080673,0.0001430486,0.0003594128,0.00005938185,0.001474533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1307048,"threshold_uncertainty_score":0.9999797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009127159877332742,"score_gpt":0.227624551667366,"score_spread":0.2184973917900333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}