{"id":"W2112374340","doi":"10.1128/mcb.21.18.6332-6345.2001","title":"S Phase-Specific Proteolytic Cleavage Is Required To Activate Stable DNA Binding by the CDP/Cut Homeodomain Protein","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Medical Research Council; Medical Research Council Canada","keywords":"Biology; Molecular biology; DNA; DNA-binding protein; Immunoprecipitation; Proteolysis; Cleavage (geology); Gene isoform; Biochemistry; Transcription factor; Cell biology; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007082699,0.0003123373,0.0002161793,0.0001362874,0.0000971443,0.0002925732,0.00009783736,0.0001785832,0.001028161],"category_scores_gemma":[0.0001133071,0.0001636317,0.0001900842,0.0001141163,0.0002207972,0.0001432566,0.0002043221,0.0003574188,0.0004651721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003952883,"about_ca_system_score_gemma":0.0002396412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000839292,"about_ca_topic_score_gemma":0.001341601,"domain_scores_codex":[0.9999189,0.00001146089,0.000006224528,0.00002100275,0.00001789353,0.00002450088],"domain_scores_gemma":[0.9998747,0.00003463934,0.00003379074,0.0000119639,0.00001381212,0.0000310547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005697898,0.00000901302,0.0002147893,0.0000158615,0.000001963245,0.00003918869,0.000008658954,0.00001962057,0.9991755,0.00003477493,0.00001603964,0.0004076133],"study_design_scores_gemma":[0.00001548154,0.0001227179,0.02068014,0.000006178253,0.000007091262,0.0002693424,0.00003917398,0.0007771305,0.9766369,0.00005238724,0.001389414,0.000003957114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970396,0.0007593938,0.001373321,0.00004064299,0.00001238523,0.00001583137,0.0002145399,0.00003662653,0.0005077036],"genre_scores_gemma":[0.9960633,0.0003713388,0.00124983,0.0000381059,0.00000572887,0.00001892646,0.0009646913,0.00002147023,0.001266694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001028161,"threshold_uncertainty_score":0.003439486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009127159877332742,"score_gpt":0.227624551667366,"score_spread":0.2184973917900333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}