{"id":"W2112392406","doi":"10.1158/1538-7445.am2011-1778","title":"Abstract 1778: Anticancer activities and regulatory effects on apoptotic gene expression of Bufalin in the orthotopic transplantation model of human colorectal cancer in nude mice","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Bufalin; Apoptosis; Transplantation; TUNEL assay; H&E stain; Colorectal cancer; Cancer; Medicine; Immunohistochemistry; Saline; Nude mouse; Pharmacology; Internal medicine; Pathology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119401,0.0005079744,0.0003009943,0.0005330523,0.0001719986,0.0001402698,0.0001990462,0.0003348658,0.002661782],"category_scores_gemma":[0.00007236943,0.0001218748,0.0002972862,0.000289133,0.0002769492,0.0002780289,0.0001029469,0.0005973928,0.0004235856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002633146,"about_ca_system_score_gemma":0.000229307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004493037,"about_ca_topic_score_gemma":0.0004678089,"domain_scores_codex":[0.9998603,0.00001866506,0.00001302367,0.00002600814,0.00004449951,0.00003755777],"domain_scores_gemma":[0.9999374,0.00000722867,0.00001854909,0.000006653853,0.000007761283,0.00002232864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006927033,0.0001617048,0.0001264461,0.00006127014,0.000003928316,0.00006672004,0.00001457454,0.00004071266,0.9969285,0.00008026802,0.0001040182,0.001719081],"study_design_scores_gemma":[0.0001048333,0.001940666,0.002546683,0.000006074736,0.00002326684,0.0002403773,0.00002739633,0.0005435586,0.992423,0.00004067119,0.002098726,0.000004678634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924154,0.002095716,0.002075134,0.0002026617,0.00009744015,0.00007665346,0.0006673746,0.0001459346,0.002223559],"genre_scores_gemma":[0.9889495,0.001670167,0.002553243,0.0001035804,0.00003721116,0.0001710439,0.001316206,0.00002535137,0.005173631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002661782,"threshold_uncertainty_score":0.008904576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0788656998403976,"score_gpt":0.3841695026609663,"score_spread":0.3053038028205687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}