{"id":"W2112523400","doi":"10.1161/circresaha.111.246371","title":"Pyridine Nucleotide Regulation of Cardiac Intermediary Metabolism","year":2012,"lang":"en","type":"review","venue":"Circulation Research","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"NAD+ kinase; Biochemistry; Pentose phosphate pathway; Oxidative phosphorylation; Beta oxidation; Mitochondrion; Intracellular; Oxidative stress; Biology; Glycolysis; Metabolism; Chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002974905,0.0002958264,0.002031269,0.0009811466,0.0001097138,0.00002754258,0.0001474182,0.0004992116,0.0008089318],"category_scores_gemma":[0.0004499226,0.000234128,0.001832566,0.00127652,0.0002491159,0.0001461999,0.0001203651,0.0009520615,0.0003302472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003327295,"about_ca_system_score_gemma":0.0004779852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006530893,"about_ca_topic_score_gemma":0.000001607747,"domain_scores_codex":[0.9958263,0.0009685329,0.0008023385,0.0004358274,0.001521044,0.0004459826],"domain_scores_gemma":[0.9973897,0.0003408404,0.0002515141,0.0009839652,0.000732236,0.0003017469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001884664,0.00007393273,0.0009205571,0.009768679,0.0009235922,0.000002472798,0.00008738785,0.000009515089,0.00004054428,0.000288539,0.001253946,0.986612],"study_design_scores_gemma":[0.000211746,0.00001817345,0.03761203,0.002685603,0.002029881,0.00003202293,0.00003132628,0.00004544243,0.0000166898,0.00002197949,0.9571159,0.0001791902],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005802224,0.9939011,0.00006641235,0.00003138803,0.001111953,0.00161707,0.00003634105,0.00006318356,0.002592331],"genre_scores_gemma":[0.01271624,0.9840409,0.00003962499,0.000005376512,0.001458609,0.00008911878,0.0008487859,0.00009538384,0.0007060221],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9864328,"threshold_uncertainty_score":0.9547464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1521714171159568,"score_gpt":0.4092822709165851,"score_spread":0.2571108538006283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}