{"id":"W2112575569","doi":"10.1158/1055-9965.epi-05-0027","title":"Statins and Cancer Development","year":2005,"lang":"en","type":"review","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Pravastatin; HMG-CoA reductase; Reductase; Mevalonate pathway; Statin; Hydroxymethylglutaryl-CoA reductase; Cholesterol synthesis; Lovastatin; Cancer; Cholesterol; Atorvastatin; Coenzyme A; Cancer research; Pharmacology; Medicine; Enzyme; Chemistry; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001374327,0.0006476747,0.001716678,0.0001643981,0.0001656754,0.00001403576,0.0003003796,0.0009131624,0.0001832802],"category_scores_gemma":[0.0001984402,0.0005765926,0.0004883042,0.0001459686,0.0002637607,0.00000959893,0.0002232852,0.0002841138,0.00001800989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002222911,"about_ca_system_score_gemma":0.001323311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001599152,"about_ca_topic_score_gemma":0.001059264,"domain_scores_codex":[0.9959846,0.0008806511,0.001193775,0.001170058,0.0001066629,0.0006642569],"domain_scores_gemma":[0.9981955,0.0001186683,0.0008886538,0.0004753723,0.00008631693,0.000235505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003641724,0.00002976842,0.0002365628,0.001612008,0.001052841,7.75165e-8,0.00002057985,0.000002309903,0.00003850668,0.00003094077,0.07403819,0.9229018],"study_design_scores_gemma":[0.0004417899,0.000051675,0.0003391054,0.002709953,0.0008053777,0.00001580626,0.0000104564,0.000002879746,0.00001044596,0.00005805817,0.9949523,0.0006021429],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004707266,0.9892783,0.0007664887,0.0001856585,0.008474859,0.0009186115,0.0001673726,0.00003012592,0.0001315051],"genre_scores_gemma":[0.000001772221,0.9777633,0.002998375,0.0003465115,0.01188242,0.001595845,0.00133864,0.00008424098,0.00398889],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9222997,"threshold_uncertainty_score":0.9996685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08436201003499254,"score_gpt":0.4200574833282387,"score_spread":0.3356954732932462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}