{"id":"W2112575569","doi":"10.1158/1055-9965.epi-05-0027","title":"Statins and Cancer Development","year":2005,"lang":"en","type":"review","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Pravastatin; HMG-CoA reductase; Reductase; Mevalonate pathway; Statin; Hydroxymethylglutaryl-CoA reductase; Cholesterol synthesis; Lovastatin; Cancer; Cholesterol; Atorvastatin; Coenzyme A; Cancer research; Pharmacology; Medicine; Enzyme; Chemistry; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004784658,0.0006571668,0.001221263,0.002112222,0.0003906696,0.001067996,0.0007046961,0.001549419,0.005172381],"category_scores_gemma":[0.000553416,0.0002613963,0.000377124,0.001983642,0.0004166863,0.0008960826,0.0008301099,0.00126506,0.004397098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001016973,"about_ca_system_score_gemma":0.0012528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00259384,"about_ca_topic_score_gemma":0.004228709,"domain_scores_codex":[0.9997751,0.00004034951,0.00002851492,0.00003893601,0.00009139544,0.00002566807],"domain_scores_gemma":[0.9998242,0.00004321831,0.00002918681,0.000009858342,0.00005922778,0.00003429005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007511212,0.00005932312,0.0004547609,0.004660744,0.00005961598,0.0004337286,0.00006892085,0.0002079924,0.001632428,0.004770191,0.03939733,0.9481798],"study_design_scores_gemma":[0.00002039961,0.00006356125,0.001247868,0.001151742,0.00003511518,0.001486171,0.00003912837,0.00003451407,0.0004063862,0.001674708,0.9938306,0.000009784182],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001324086,0.9976501,0.00007017095,0.0004136205,0.0001522239,0.000003798372,0.00001428682,0.000007407215,0.001556041],"genre_scores_gemma":[0.0008296845,0.9972223,0.0001082625,0.0002047266,0.0001490653,0.000006590265,0.0000279658,9.936139e-7,0.001450459],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005172381,"threshold_uncertainty_score":0.01730329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08436201003499254,"score_gpt":0.4200574833282387,"score_spread":0.3356954732932462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}