{"id":"W2112601022","doi":"10.1084/jem.193.2.181","title":"Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection","year":2001,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CTL*; Epitope; Cytotoxic T cell; Biology; Virology; Immunology; Major histocompatibility complex; Human leukocyte antigen; Immune system; Antigen; Chronic infection; Viral load; Virus; CD8; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005965093,0.0001993825,0.0002904869,0.000347984,0.0002112501,0.0004727742,0.000199211,0.0004642672,0.001319572],"category_scores_gemma":[0.001287783,0.0001897697,0.0001276127,0.0001297401,0.0003447651,0.0002755286,0.0004097977,0.0004141931,0.0004188666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001486172,"about_ca_system_score_gemma":0.000117204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001855529,"about_ca_topic_score_gemma":0.0002135556,"domain_scores_codex":[0.9995846,0.0001090798,0.00004678292,0.00008430785,0.00004875592,0.0001264135],"domain_scores_gemma":[0.9991655,0.0003859366,0.0001034527,0.00008271183,0.00009291952,0.0001694032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003641822,0.0003458813,0.3812165,0.0002107073,0.00005873918,0.0008746093,0.001821927,0.0001851134,0.5745724,0.0004215733,0.0002320308,0.03641872],"study_design_scores_gemma":[0.0001970898,0.004399305,0.9452553,0.00007757607,0.00007500488,0.00572635,0.0009958139,0.0004650309,0.04058982,0.0005360324,0.001655344,0.00002746034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986209,0.000663584,0.0001510876,0.000009976492,0.000003442205,0.00001206969,0.00003445188,0.000004381173,0.0005000902],"genre_scores_gemma":[0.9992235,0.0002048067,0.0001152908,0.00005690102,0.00001175269,0.0000221936,0.0001074924,0.000002717971,0.0002553412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001319572,"threshold_uncertainty_score":0.00441438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02565132993882911,"score_gpt":0.2891447427832347,"score_spread":0.2634934128444055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}