{"id":"W2112601022","doi":"10.1084/jem.193.2.181","title":"Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection","year":2001,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CTL*; Epitope; Cytotoxic T cell; Biology; Virology; Immunology; Major histocompatibility complex; Human leukocyte antigen; Immune system; Antigen; Chronic infection; Viral load; Virus; CD8; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003619567,0.0001072923,0.0003263542,0.0002063169,0.00004272942,0.000002615121,0.0001119643,0.00005886599,0.0007149864],"category_scores_gemma":[0.000008752681,0.00005965314,0.00003078491,0.000158009,0.0004101904,0.00006636055,0.00003229049,0.000281495,0.00002428173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001381798,"about_ca_system_score_gemma":0.00003150271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001165486,"about_ca_topic_score_gemma":0.00008980327,"domain_scores_codex":[0.9990094,0.0002318633,0.0003965955,0.00008294013,0.00008069248,0.00019852],"domain_scores_gemma":[0.9995647,0.0001271475,0.0001609328,0.00009486134,0.00002375659,0.00002860023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001149072,0.0003045839,0.03614031,0.000003423467,0.00007053016,0.00007394693,0.001849469,0.000001494883,0.9593748,0.00002319298,0.0003846162,0.0006245197],"study_design_scores_gemma":[0.006507786,0.002500436,0.1322407,0.0002100299,0.00002240344,0.0004529885,0.001641746,0.000002938518,0.8556932,0.00002314456,0.0006392619,0.00006540895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979454,0.01962558,0.00002573688,0.0002956313,0.0002179133,0.0001504776,0.000006433694,0.000002295863,0.0002219216],"genre_scores_gemma":[0.9893108,0.01047889,0.000006429107,0.000007987095,0.00006830577,0.000002249221,0.000005780757,0.000004706525,0.0001148605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1036817,"threshold_uncertainty_score":0.7828599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02565132993882911,"score_gpt":0.2891447427832347,"score_spread":0.2634934128444055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}