{"id":"W2112708847","doi":"10.15252/emmm.201404169","title":"Defective NOD2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance","year":2015,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute; McMaster University","funders":"Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Canadian Diabetes Association","keywords":"Nod; Insulin resistance; Inflammation; Dysbiosis; Adipose tissue; NOD mice; Biology; Internal medicine; Endocrinology; Immunology; Gut flora; Insulin; Diabetes mellitus; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004178772,0.0002163148,0.0002530946,0.00007438828,0.00009580131,0.00001614652,0.00009921498,0.0001628111,0.000005218905],"category_scores_gemma":[0.0004910908,0.0001924601,0.00003686869,0.000156312,0.0001465918,0.000005661851,0.0000877135,0.0001474498,0.000007222669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000396276,"about_ca_system_score_gemma":0.0001635421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007923262,"about_ca_topic_score_gemma":0.0002149952,"domain_scores_codex":[0.9986613,0.0001351474,0.0002853895,0.0004343427,0.0001885945,0.0002951744],"domain_scores_gemma":[0.9989871,0.00001282376,0.0001297958,0.0003497992,0.0002647592,0.0002557199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001624263,0.00001480232,0.0002563613,0.00005305301,0.00004259935,0.00002341315,0.0007006691,0.00000176554,0.9955347,0.0001492619,0.00162519,0.001435814],"study_design_scores_gemma":[0.004704257,0.002270651,0.01240083,0.0004051368,0.000124787,0.0001236635,0.001084576,0.00006644078,0.933152,0.001127732,0.04384843,0.0006915212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877787,0.004272725,0.001669049,0.003327394,0.0001507473,0.0003684174,0.00000531925,0.0000266083,0.002401012],"genre_scores_gemma":[0.9967361,0.0001459716,0.001596611,0.0007988369,0.0003710613,0.000006539548,0.0001176629,0.00003369993,0.0001935281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06238268,"threshold_uncertainty_score":0.7848296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504740897283248,"score_gpt":0.2686403866297465,"score_spread":0.2535929776569141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}