{"id":"W2112708847","doi":"10.15252/emmm.201404169","title":"Defective NOD2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance","year":2015,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute; McMaster University","funders":"Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Canadian Diabetes Association","keywords":"Nod; Insulin resistance; Inflammation; Dysbiosis; Adipose tissue; NOD mice; Biology; Internal medicine; Endocrinology; Immunology; Gut flora; Insulin; Diabetes mellitus; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001734594,0.0003670396,0.0002256453,0.0003538028,0.0001158843,0.0003719238,0.000133522,0.0002999954,0.001039942],"category_scores_gemma":[0.000130673,0.0002231605,0.0001775867,0.0001932664,0.0003132761,0.0001931627,0.0003389022,0.0005738168,0.0002006911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002005943,"about_ca_system_score_gemma":0.0001274106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000187203,"about_ca_topic_score_gemma":0.0003258863,"domain_scores_codex":[0.9998368,0.00004245056,0.00001514312,0.00003570546,0.00003547114,0.00003431381],"domain_scores_gemma":[0.9998469,0.00001335128,0.0000503097,0.00001580151,0.00000834491,0.0000652618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006622987,0.00005700898,0.001846985,0.00002318609,0.000008952836,0.000161618,0.0000148493,0.00004513559,0.9960737,0.0001241415,0.00004325803,0.0009389233],"study_design_scores_gemma":[0.000207872,0.001228732,0.1415593,0.0000362598,0.00007877324,0.002952259,0.0002401478,0.003090445,0.8469775,0.0007499279,0.002855588,0.00002313724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980212,0.0004850313,0.0008132473,0.0000825138,0.00001394791,0.000005249557,0.00009238517,0.00003797302,0.0004484125],"genre_scores_gemma":[0.9978905,0.0004462239,0.0006875686,0.00004905227,0.000005992289,0.00001246233,0.000116827,0.00001204355,0.0007793847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001039942,"threshold_uncertainty_score":0.003479004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504740897283248,"score_gpt":0.2686403866297465,"score_spread":0.2535929776569141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}