{"id":"W2112737937","doi":"10.1128/jvi.03478-12","title":"A Doubly Fluorescent HIV-1 Reporter Shows that the Majority of Integrated HIV-1 Is Latent Shortly after Infection","year":2013,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; Jurkat cells; Long terminal repeat; Gene silencing; Virology; Vector (molecular biology); Latency (audio); Human immunodeficiency virus (HIV); Cell culture; Genetics; T cell; Gene; Recombinant DNA; Gene expression; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004629994,0.0001716908,0.0004080114,0.0001761062,0.00007780774,0.00001742594,0.0001891316,0.0002569023,0.005390334],"category_scores_gemma":[0.00005934017,0.00009215184,0.0002543548,0.00009488002,0.0003178464,0.0001412565,0.00008149661,0.0005851843,0.0007583521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008802938,"about_ca_system_score_gemma":0.0001136898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003254221,"about_ca_topic_score_gemma":0.00009013792,"domain_scores_codex":[0.9983999,0.0003667581,0.0006111583,0.0001683827,0.00009351024,0.0003602517],"domain_scores_gemma":[0.9988117,0.0001001366,0.0004452875,0.0002917753,0.0002956999,0.00005537234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001838837,0.0008194744,0.7674475,0.00002145412,0.001448327,0.0002129729,0.0008174405,0.000009285734,0.1435702,0.00002687347,0.07618251,0.007605038],"study_design_scores_gemma":[0.002734171,0.001762671,0.8894997,0.00004110203,0.0002077892,0.002074253,0.0001058027,0.00001286301,0.04784476,0.0002686681,0.05530117,0.0001470619],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935474,0.00128163,0.0002356067,0.003842429,0.0005180071,0.0002990006,0.00005516268,0.000009007858,0.0002117427],"genre_scores_gemma":[0.9979573,0.0002905959,0.00005699855,0.0003857467,0.00005553595,0.00003475959,0.00003319061,0.00001095635,0.001174905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1220521,"threshold_uncertainty_score":0.9955189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01695563531132482,"score_gpt":0.2503758318926706,"score_spread":0.2334201965813458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}