{"id":"W2112759994","doi":"10.1128/iai.00161-06","title":"Alcohol Dehydrogenase Restricts the Ability of the Pathogen <i>Candida albicans</i> To Form a Biofilm on Catheter Surfaces through an Ethanol-Based Mechanism","year":2006,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Stanford Diabetes Research Center; National Institute of Allergy and Infectious Diseases; Bristol-Myers Squibb","keywords":"Biofilm; Candida albicans; Microbiology; Corpus albicans; Alcohol dehydrogenase; In vivo; Biology; In vitro; Ethanol; Acetaldehyde; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000595813,0.0001567161,0.0002172435,0.00003637261,0.0003759204,0.00002168441,0.0001075424,0.0001089612,0.00004777066],"category_scores_gemma":[0.0001684797,0.00008617873,0.0001422905,0.0003195643,0.00019299,0.0001060061,0.00004328936,0.000285702,0.000004714984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007524276,"about_ca_system_score_gemma":0.00009643231,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01006514,"about_ca_topic_score_gemma":0.001974165,"domain_scores_codex":[0.9987842,0.0002949639,0.0002698235,0.0002239094,0.0002315577,0.0001955687],"domain_scores_gemma":[0.9987954,0.0001391424,0.0001040153,0.0007728096,0.0001229611,0.00006566534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006834535,0.001177373,0.1642615,0.00009029666,0.00003477514,0.000002049453,0.0007296208,0.00005906536,0.8307617,0.0007675641,0.0001433491,0.001289254],"study_design_scores_gemma":[0.0007503166,0.0008483669,0.6636391,0.00005873664,0.00006308962,0.000006321953,0.000110524,0.0001436752,0.3308845,0.0016941,0.001685729,0.0001154906],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996172,0.00005194942,0.0003078372,0.0007094888,0.0001030056,0.0006756894,0.00005375517,0.00004053965,0.001885752],"genre_scores_gemma":[0.9986873,0.00003263954,0.00006037562,0.001077463,0.0000308482,0.00002087759,0.0000184246,0.00001186308,0.00006024128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4998772,"threshold_uncertainty_score":0.9965269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02344611936264741,"score_gpt":0.283554618830219,"score_spread":0.2601084994675716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}