{"id":"W2112759994","doi":"10.1128/iai.00161-06","title":"Alcohol Dehydrogenase Restricts the Ability of the Pathogen <i>Candida albicans</i> To Form a Biofilm on Catheter Surfaces through an Ethanol-Based Mechanism","year":2006,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Stanford Diabetes Research Center; National Institute of Allergy and Infectious Diseases; Bristol-Myers Squibb","keywords":"Biofilm; Candida albicans; Microbiology; Corpus albicans; Alcohol dehydrogenase; In vivo; Biology; In vitro; Ethanol; Acetaldehyde; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001716049,0.0003895871,0.0002619078,0.0001249157,0.00007573933,0.0005127777,0.0002549325,0.0001850881,0.000781959],"category_scores_gemma":[0.0002266512,0.000167792,0.0002090279,0.0001036723,0.0002795961,0.0001839374,0.000242926,0.000438626,0.0002601907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003225908,"about_ca_system_score_gemma":0.000198893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001329819,"about_ca_topic_score_gemma":0.001409584,"domain_scores_codex":[0.9997854,0.00004315807,0.00002256283,0.00003378056,0.00006979152,0.00004536803],"domain_scores_gemma":[0.9998044,0.00004084004,0.00006701481,0.00002383769,0.00003364017,0.00003036057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005790756,0.00001844993,0.000204299,0.00002024275,0.000003890717,0.00001151664,0.000003815864,0.00002267383,0.9989894,0.00001709845,0.00001557833,0.0006351046],"study_design_scores_gemma":[0.000006721387,0.0002737808,0.006229976,0.000004214616,0.00001734106,0.000125621,0.00002078127,0.0005024173,0.992153,0.00001532917,0.0006472669,0.000003564925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945574,0.001896193,0.002352169,0.0001072338,0.00002063886,0.00001903005,0.0001368599,0.00007224504,0.0008381659],"genre_scores_gemma":[0.9960864,0.0008999837,0.001739698,0.0000658325,0.000009832424,0.00001338722,0.0001962049,0.00002367519,0.0009650537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001329819,"threshold_uncertainty_score":0.002644181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02344611936264741,"score_gpt":0.283554618830219,"score_spread":0.2601084994675716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}